PCSK6 蛋白, Human (HEK293, hFc)

The PCSK6 protein is a serine endoprotease that plays a key role in preprotein processing by cleavage at sites with paired basic amino acids, specifically recognizing the RXXX[KR]R consensus motif. Its function may be involved in the constitutive secretory pathway, with a unique and limited distribution in neuroendocrine and non-neuroendocrine tissues. PCSK6 Protein, Human (HEK293, hFc) is the recombinant human-derived PCSK6 protein, expressed by HEK293 , with C-hFc labeled tag. The total length of PCSK6 Protein, Human (HEK293, hFc) is 110 a.a., with molecular weight of 48 kDa.

PCSK6 蛋白是一种丝氨酸内切蛋白酶，通过在以配对碱性氨基酸为特征的位点进行切割，特别识别 RXXX[KR]R 共有基序，在多种前蛋白的加工中发挥着关键作用。其功能参与可能与组成型分泌途径有关，在神经内分泌和非神经内分泌组织中表现出独特且有限的分布。该酶在特定基序处精确切割底物的能力凸显了其在各种细胞环境中前蛋白的调节加工中的重要性。

The enzyme activity of this recombinant protein is testing in progress, we cannot offer a guarantee yet.

Human

HEK293

C-hFc

P29122 (R860-G969)

5046  [NCBI]

REECIHCAKNFHFHDWKCVPACGEGFYPEEMPGLPHKVCRRCDENCLSCAGSSRNCSRCKTGFTQLGTSCITNHTCSNADETFCEMVKSNRLCERKLFIQFCCRTCLLAG

48 kDa

Greater than 90% as determined by reducing SDS-PAGE.

无菌粉末.

Lyophilized from a 0.2 μm filtered solution of PBS, 6% Trehalose, pH 7.4.

<1 EU/μg, determined by LAL method.

It is not recommended to reconstitute to a concentration less than 100 μg/mL in ddH₂O.

Stored at -20°C for 2 years. After reconstitution, it is stable at 4°C for 1 week or -20°C for longer (with carrier protein). It is recommended to freeze aliquots at -20°C or -80°C for extended storage.

Room temperature in continental US; may vary elsewhere.