1. 重组蛋白
  2. Immune Checkpoint Proteins CD Antigens
  3. Inhibitory Checkpoint Molecules Macrophage CD Proteins Monocyte CD Proteins Dendritic Cell CD Proteins
  4. B7-DC/PD-L2 B7-DC/CD273
  5. PD-L2 蛋白, Mouse (200a.a, HEK293, Fc)

PD-L2 蛋白, Mouse (200a.a, HEK293, Fc)

目录号: HY-P72491
产品使用指南

PD-L2 蛋白在 T 细胞共刺激信号中发挥着关键作用,独立于 PDCD1 促进增殖和 IFNG 产生。虽然与 PDCD1 相互作用会抑制 T 细胞增殖,但 PD-L2 本身会复杂地促进免疫反应。这种动态相互作用强调了 PD-L2 在免疫信号网络内促进或抑制 T 细胞激活的双重作用,展示了复杂的调节机制。PD-L2 蛋白, Mouse (200a.a, HEK293, Fc) 是重组的 PD-L2 蛋白,由 HEK293 表达,带有 C-hFc 标签。PD-L2 蛋白, Mouse (200a.a, HEK293, Fc) 全长 200 个氨基酸,分子量为 70-80 kDa。

MCE 的所有产品仅用作科学研究或药证申报,我们不为任何个人用途提供产品和服务

重组蛋白定制服务

1.  客户无需承担相应的运输费用。

2.  同一机构(单位)同一产品试用装仅限申领一次,同一机构(单位)一年内

     可免费申领三个不同产品的试用装。

3.  试用装只面向终端客户

规格 是否有货
50 μg   询价  
100 μg   询价  

* Please select Quantity before adding items.

注册 MCE会员完成审核
即刻享有 积分商城 300 专属积分

Top Publications Citing Use of Products
  • 生物活性

  • 技术参数

  • 产品性质

  • 产品资料

描述

PD-L2 Protein plays a critical role in the T-cell costimulatory signal, fostering proliferation and IFNG production independently of PDCD1. While interacting with PDCD1 inhibits T-cell proliferation, PD-L2 itself intricately promotes immune responses. The dynamic interplay emphasizes PD-L2's dual role in either promoting or inhibiting T-cell activation within the immune signaling network, showcasing intricate regulatory mechanisms. PD-L2 Protein, Mouse (200a.a, HEK293, Fc) is the recombinant mouse-derived PD-L2 protein, expressed by HEK293 , with C-hFc labeled tag. The total length of PD-L2 Protein, Mouse (200a.a, HEK293, Fc) is 200 a.a., with molecular weight of 70-80 kDa.

研究背景

PD-L2 蛋白在 T 细胞增殖和 IFNG 产生所需的共刺激信号中发挥着关键作用,以不依赖 PDCD1 的方式发挥作用。虽然它与 PDCD1 的相互作用可以通过阻碍细胞周期进程和细胞因子产生来抑制 T 细胞增殖,但 PD-L2 本身错综复杂地参与促进这些免疫反应。PD-L2 和 PDCD1 之间的动态相互作用凸显了起作用的调节机制,强调了该蛋白质基于其在免疫信号网络内的相互作用在促进或抑制 T 细胞激活方面的双重作用。

种属

Mouse

表达系统

HEK293

标签

C-hFc

蛋白编号

Q9WUL5 (L20-R219)

基因 ID

58205  [NCBI]

蛋白结构
N-term
PD-L2 (L20-R219)
Accession # Q9WUL5
hFc
C-term
同用名
Programmed cell death 1 ligand 2; Pdcd1lg2; PD-1 ligand 2; PD-L2; PDCD1 ligand 2; B7-DC; CD273
氨基酸序列

LFTVTAPKEVYTVDVGSSVSLECDFDRRECTELEGIRASLQKVENDTSLQSERATLLEEQLPLGKALFHIPSVQVRDSGQYRCLVICGAAWDYKYLTVKVKASYMRIDTRILEVPGTGEVQLTCQARGYPLAEVSWQNVSVPANTSHIRTPEGLYQVTSVLRLKPQPSRNFSCMFWNAHMKELTSAIIDPLSRMEPKVPR

分子量

70-80 kDa

纯度

Greater than 95% as determined by reducing SDS-PAGE.

内毒素含量

<1 EU/μg, determined by LAL method.

文件资料
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

  • 复溶计算器

  • 重组蛋白稀释计算器

  • 比活力计算器

The reconstitution calculator equation

Volume (to add to vial) = Mass (in vial) ÷ Desired Reconstitution Concentration

Volume (to add to vial) = Mass (in vial) ÷ Desired Reconstitution Concentration
= ÷

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2

The specific activity calculator equation

Specific Activity (Unit/mg) = 106 ÷ Biological Activity (ED50)

Specific Activity (Unit/mg) = 106 ÷ Biological Activity (ED50)
Unit/mg = 106 ÷ ng/mL

您最近查看的产品:

Your information is safe with us. * Required Fields.

   产品名称:

 

* 需求量:

* 客户姓名:

 

* Email:

* 电话:

 

* 公司或机构名称:

   留言给我们:

Bulk Inquiry

Inquiry Information

产品名称:
PD-L2 Protein, Mouse (200a.a, HEK293, Fc)
目录号:
HY-P72491
需求量: