2. 重组蛋白
  3. Cytokines and Growth Factors
  4. PDGFs & PDGFRs
  5. PDGF
  6. PDGF-B
  7. PDGF-BB 蛋白, Cynomolgus (HEK293, Fc)

PDGF-BB 蛋白, Cynomolgus (HEK293, Fc)

目录号: HY-P75966
COA 产品使用指南

PDGF-BB是一种常在肿瘤中过度表达的生长因子，是一种新型的强效淋巴管生成因子。PDGF-BB 蛋白, Cynomolgus (HEK293, Fc) 是重组的 PDGF-BB 蛋白，由 HEK293 表达，带有 N-mFc 标签。PDGF-BB 蛋白, Cynomolgus (HEK293, Fc) 全长 109 个氨基酸，分子量分别约为 ~43 & 32 kDa。

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规格 价格 是否有货 数量
Free Sample   Apply now  
5 μg ￥550 In-stock
10 μg ￥950 In-stock
50 μg ￥2600 In-stock
100 μg   询价  

* Please select Quantity before adding items.

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描述

PDGF-BB is a growth factor frequently overexpressed in cancers, are novel potent lymphangiogenic factors. PDGF-BB Protein, Cynomolgus (HEK293, Fc) is the recombinant cynomolgus-derived PDGF-BB protein, expressed by HEK293 , with N-mFc labeled tag. The total length of PDGF-BB Protein, Cynomolgus (HEK293, Fc) is 109 a.a., with molecular weight of ~43 & 32 kDa, respectively.
研究背景

PDGF-BB 是一种常在肿瘤中过度表达的生长因子，是一种新型的强效淋巴管生成因子。PDGF-BB 是一种有效的多效因子，通过以下 3 种机制促进肿瘤生长和转移:直接刺激肿瘤细胞生长；刺激血管生成；刺激淋巴管生成和转移[1]。
种属

Cynomolgus
表达系统

HEK293
标签

N-mFc
蛋白编号

EHH65851 (S82-P190)
基因 ID

/
蛋白结构
N-term
mFc
PDGF-BB (S82-P190)
Accession # EHH65851
C-term
同用名
Platelet-derived growth factor subunit B; PDGF-2; PDGFB
分子量

Approximately 43&32 kDa
纯度

Greater than 95% as determined by reducing SDS-PAGE
性状

无菌粉末.
组分

Lyophilized from a 0.2 μm filtered solution of PBS, pH 7.4. Normally 5 % - 8 % trehalose, mannitol and 0.01% Tween 80 are added as protectants before lyophilization.
内毒素含量

<1 EU/μg, determined by LAL method.
复溶方法

It is not recommended to reconstitute to a concentration less than 100 μg/mL in ddH2O.
保存条件 & 期限

Stored at -20°C for 2 years. After reconstitution, it is stable at 4°C for 1 week or -20°C for longer (with carrier protein). It is recommended to freeze aliquots at -20°C or -80°C for extended storage.
运输条件

Shipping with dry ice.
文件资料

COA (210 KB)

产品使用指南 (1213 KB)

PDGF-BB Protein, Cynomolgus (HEK293, Fc) 相关分类

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

  • 复溶计算器

  • 重组蛋白稀释计算器

  • 比活力计算器

The reconstitution calculator equation

Volume (to add to vial) = Mass (in vial) ÷ Desired Reconstitution Concentration

Volume (to add to vial) = Mass (in vial) ÷ Desired Reconstitution Concentration
= ÷

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2

The specific activity calculator equation

Specific Activity (Unit/mg) = 106 ÷ Biological Activity (ED50)

Specific Activity (Unit/mg) = 106 ÷ Biological Activity (ED50)
Unit/mg = 106 ÷ ng/mL

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目录号：
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