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  3. Periostin 蛋白, Human (781a.a, HEK293, His)

Periostin 蛋白, Human (781a.a, HEK293, His)

目录号: HY-P74638
产品使用指南

骨膜蛋白 (POSTN) 是一种细胞外基质分泌蛋白,在包括心肌梗死后的组织发育和再生中起作用,包括伤口愈合和心室重构。POSTN 与整合素和 BMP1 结合,支持细胞粘附、细胞迁移,与结缔组织的结构完整性。Periostin 蛋白, Human (781a.a, HEK293, His) 是重组的 骨膜素蛋白,由 HEK293 表达,带有 C-His 标签。Periostin 蛋白, Human (781a.a, HEK293, His) 全长 781 个氨基酸,分子量为 66-80 kDa。

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描述

Periostin (POSTN) is a secreted extracellular matrix protein that functions in tissue development and regeneration, including wound healing, and ventricular remodeling following myocardial infarction. POSTN binds to integrins and BMP1 to support cell adhesion, cell migration and the structural integrity of connective tissues. Periostin Protein, Human (781a.a, HEK293, His) is the recombinant human-derived Periostin protein, expressed by HEK293 , with C-His labeled tag. The total length of Periostin Protein, Human (781a.a, HEK293, His) is 781 a.a., with molecular weight of 66-80 kDa.

研究背景

骨膜蛋白 (POSTN) 是一种细胞外基质分泌蛋白,在包括心肌梗死后的组织发育和再生中起作用,包括伤口愈合和心室重构。POSTN 与整合素结合,支持上皮细胞的粘附和迁移,POSTN 还增强与 BMP1 在结缔组织纤维连接蛋白基质中的结合,以及随后赖氨酸氧化酶的蛋白水解激活,进而促进结缔组织的结构完整性。POSTN 在癌症干细胞的维持和转移中起作用。缺乏 POSTN 会导致心脏瓣膜疾病、骨骼和牙齿缺陷[1][2]

种属

Human

表达系统

HEK293

标签

C-His

蛋白编号

B1ALD9 (M1-Q781)

基因 ID
蛋白结构
N-term
Periostin (M1-Q781)
Accession # B1ALD9
His
C-term
同用名
Osteoblast-specific factor 2; OSF-2; POSTN; Periostin
分子量

66-80 kDa

纯度

Greater than 95% as determined by reducing SDS-PAGE

内毒素含量

<1 EU/μg, determined by LAL method.

文件资料

Periostin Protein, Human (781a.a, HEK293, His) 相关分类

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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The reconstitution calculator equation

Volume (to add to vial) = Mass (in vial) ÷ Desired Reconstitution Concentration

Volume (to add to vial) = Mass (in vial) ÷ Desired Reconstitution Concentration
= ÷

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2

The specific activity calculator equation

Specific Activity (Unit/mg) = 106 ÷ Biological Activity (ED50)

Specific Activity (Unit/mg) = 106 ÷ Biological Activity (ED50)
Unit/mg = 106 ÷ ng/mL

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Periostin Protein, Human (781a.a, HEK293, His)
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HY-P74638
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