Peroxiredoxin-2/PRDX2 蛋白, Human (sf9, His)

Peroxiredoxin-2 (PRDX2) is a thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides, which is essential for cellular protection against oxidative stress. It detoxifies peroxide, senses hydrogen peroxide-mediated signaling events, and may participate in signaling cascades initiated by growth factors and tumor necrosis factor-alpha. Peroxiredoxin-2/PRDX2 Protein, Human (sf9, His) is the recombinant human-derived Peroxiredoxin-2/PRDX2 protein, expressed by Sf9 insect cells , with N-His labeled tag. The total length of Peroxiredoxin-2/PRDX2 Protein, Human (sf9, His) is 198 a.a., with molecular weight of ~27 kDa.

Peroxiredoxin-2 (PRDX2) 是一种硫醇特异性过氧化物酶，可作为还原过氧化氢和有机氢过氧化物的催化剂，将它们分别转化为水和醇。它在细胞保护免受氧化应激方面的重要作用涉及对过氧化物进行解毒并充当过氧化氢介导的信号事件的传感器。PRDX2 还可能参与由生长因子和肿瘤坏死因子-α 启动的信号级联反应，从而可能影响细胞内 H(2)O(2) 浓度。这种多功能蛋白质强调了其在细胞氧化还原调节和应激反应途径中的重要性。

Measured by its ability to reduce H₂O₂ and the specific activity is >300 pmoles/min/μg.

Human

Sf9 insect cells

N-His

P32119 (M1-N198)

7001  [NCBI]

Approximately 27 kDa

Greater than 90% as determined by reducing SDS-PAGE

溶液.

Supplied as a 0.2 μm filtered solution of 50 mM Tris, 100 mM NaCl, pH 8.0, 10% gly.

<1 EU/μg, determined by LAL method.

N/A.

Stored at -80°C for 1 year. It is stable at -20°C for 3 months after opening. It is recommended to freeze aliquots at -80°C for extended storage. Avoid repeated freeze-thaw cycles.

Shipping with dry ice.