Persephin 蛋白, Human

Persephin protein is a disulfide-linked homodimer with neurotrophic activity that specifically benefits midbrain dopaminergic and motor neurons. Its unique ability to target these populations suggests that it plays a special role in supporting their survival and function. Persephin Protein, Human is the recombinant human-derived Persephin protein, expressed by E. coli , with tag free. The total length of Persephin Protein, Human is 96 a.a., with molecular weight of ~12.0 kDa.

Persephin 蛋白是一种通过二硫键形成的同二聚体，具有专门针对中脑多巴胺能和运动神经元的神经营养活性。Persephin 对这些特定神经元群体发挥其神经营养作用的独特能力表明其在支持和促进多巴胺能神经元和运动神经元的存活或功能方面具有特殊作用。同二聚体结构突出了二硫键在维持 Persephin 完整性和功能方面的重要性，强调了其对中脑区域神经元发育和维护的潜在影响。

Human

E. coli

Tag Free

O60542 (A61-G156)

5623  [NCBI]

ALSGPCQLWSLTLSVAELGLGYASEEKVIFRYCAGSCPRGARTQHGLALARLQGQGRAHGGPCCRPTRYTDVAFLDDRHRWQRLPQLSAAACGCGG

Approximately 12.0 kDa

Greater than 95% as determined by reducing SDS-PAGE.

无菌粉末.

Lyophilized from a 0.2 μm filtered solution of 4 mM HCl.

<1 EU/μg, determined by LAL method.

It is not recommended to reconstitute to a concentration less than 100 μg/mL in ddH₂O. For long term storage it is recommended to add a carrier protein (0.1% BSA, 5% HSA, 10% FBS or 5% Trehalose).

Stored at -20°C for 2 years. After reconstitution, it is stable at 4°C for 1 week or -20°C for longer (with carrier protein). It is recommended to freeze aliquots at -20°C or -80°C for extended storage.

Room temperature in continental US; may vary elsewhere.