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  3. PLAU/uPA 蛋白, Mouse (HEK293, C-His-Avi)

PLAU/uPA 蛋白, Mouse (HEK293, C-His-Avi)

目录号: HY-P78017
产品使用指南

PLAU 或尿激酶型纤溶酶原激活剂 (uPA) 通过裂解纤溶酶原形成活性纤溶酶来关键启动纤维蛋白溶解。这种酶促转化对于调节凝块溶解和组织重塑至关重要。PLAU/uPA 蛋白, Mouse (HEK293, C-His-Avi) 是重组的 PLAU/uPA 蛋白,由 HEK293 表达,带有 C-His-Avi 标签。PLAU/uPA 蛋白, Mouse (HEK293, C-His-Avi) 全长 413 个氨基酸,分子量为 30-35 kDa。

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描述

PLAU or urokinase-type plasminogen activator (uPA) critically initiates fibrinolysis by cleaving plasminogen to form active plasmin. This enzymatic conversion is critical for regulating clot dissolution and tissue remodeling. PLAU/uPA Protein, Mouse (HEK293, C-His-Avi) is the recombinant mouse-derived PLAU/uPA protein, expressed by HEK293 , with C-His-Avi labeled tag. The total length of PLAU/uPA Protein, Mouse (HEK293, C-His-Avi) is 413 a.a., with molecular weight of 30-35 kDa.

研究背景

PLAU,也称为尿激酶型纤溶酶原激活剂(uPA),通过特异性裂解酶原纤溶酶原生成活性酶纤溶酶,在纤维蛋白溶解中发挥至关重要的作用。这种酶促转化是调节血凝块溶解和组织重塑的关键步骤。PLAU 激活纤溶酶的能力启动一系列蛋白水解事件,有助于纤维蛋白凝块和细胞外基质成分的分解。这一过程对于各种生理功能至关重要,包括伤口愈合、组织修复和血栓溶解。

种属

Mouse

表达系统

HEK293

标签

C-Avi;C-His

蛋白编号

P06869 (G21-F433)

基因 ID

18792  [NCBI]

蛋白结构
N-term
PLAU (G21-F433)
Accession # P06869
His
C-term
同用名
PLAU; Urokinase; ATF; UPA; URK; u-PA; BDPLT5; QPD
分子量

30-35 kDa

纯度

Greater than 95% as determined by Tris-Bis PAGE.

内毒素含量

<1 EU/μg, determined by LAL method.

文件资料

PLAU/uPA Protein, Mouse (HEK293, C-His-Avi) 相关分类

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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The reconstitution calculator equation

Volume (to add to vial) = Mass (in vial) ÷ Desired Reconstitution Concentration

Volume (to add to vial) = Mass (in vial) ÷ Desired Reconstitution Concentration
= ÷

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2

The specific activity calculator equation

Specific Activity (Unit/mg) = 106 ÷ Biological Activity (ED50)

Specific Activity (Unit/mg) = 106 ÷ Biological Activity (ED50)
Unit/mg = 106 ÷ ng/mL

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产品名称:
PLAU/uPA Protein, Mouse (HEK293, C-His-Avi)
目录号:
HY-P78017
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