PLXDC2 蛋白, Mouse (HEK293, His)

The PLXDC2 protein is associated with tumor angiogenesis, suggesting its potential role in blood vessel growth in the tumor microenvironment. The specific mechanism and downstream signaling pathways by which PLXDC2 promotes tumor angiogenesis need to be further elucidated, thus prompting people to explore its role in promoting vascularization during tumorigenesis. PLXDC2 Protein, Mouse (HEK293, His) is the recombinant mouse-derived PLXDC2 protein, expressed by HEK293 , with C-6*His labeled tag. The total length of PLXDC2 Protein, Mouse (HEK293, His) is 425 a.a., with molecular weight of ~70-90 kDa.

PLXDC2 蛋白与肿瘤血管生成有关，表明它可能参与与肿瘤微环境内血管生长相关的复杂过程。PLXDC2促进肿瘤血管生成的具体机制及其下游信号通路仍有待充分阐明，有必要进一步研究其在肿瘤发生过程中促进血管形成的作用。值得注意的是，PLXDC2 与 CTTN 相互作用，表明潜在的分子关联可能有助于其在肿瘤相关血管生成过程中的功能。PLXDC2 在肿瘤血管生成中的作用及其与其他细胞成分的相互作用的复杂性强调了深入探索的必要性，以更好地了解其对癌症进展的贡献。

Immobilized Mouse PLXDC2 at 2 μg/mL (100 μL/well) can bind Anti-PLXDC2 Antibody, The ED₅₀ for this effect is 1.749 μg/mL.

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  Immobilized Mouse PLXDC2 at 2 μg/mL (100 μL/well) can bind Anti-PLXDC2 Antibody, The ED₅₀ for this effect is 1.749 μg/mL.

Mouse

HEK293

C-6*His

Q9DC11 (E31-A455)

67448  [NCBI]

EPGHHTNDWIYEVTNAFPWNEEGVEVDSQAYNHRWKRNVDPFKAVDTNRASMGQASPESKGFTDLLLDDGQDNNTQIEEDTDHNYYISRIYGPADSASRDLWVNIDQMEKDKVKIHGILSNTHRQAARVNLSFDFPFYGHFLNEVTVATGGFIYTGEVVHRMLTATQYIAPLMANFDPSVSRNSTVRYFDNGTALVVQWDHVHLQDNYNLGSFTFQATLLMDGRIIFGYKEIPVLVTQISSTNHPVKVGLSDAFVVVHRIQQIPNVRRRTIYEYHRVELQMSKITNISAVEMTPLPTCLQFNGCGPCVSSQIGFNCSWCSKLQRCSSGFDRHRQDWVDSGCPEEVQSKEKMCEKTEPGETSQTTTTSHTTTMQFRVLTTTRRAVTSQMPTSLPTEDDTKIALHLKDSGASTDDSAAEKKGGTLHA

Approximately 70-90 kDa

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  Greater than 95% as determined by reducing SDS-PAGE.

无菌粉末

Lyophilized from a 0.2 μm filtered solution of 20 mM Glycine-HCl, 10% Trehalose, 0.05% Tween 80, pH 3.5 or PBS, pH 7.4.

<1 EU/μg, determined by LAL method.

It is not recommended to reconstitute to a concentration less than 100 μg/mL in ddH₂O. For long term storage it is recommended to add a carrier protein (0.1% BSA, 5% HSA, 10% FBS or 5% Trehalose).

Stored at -20°C for 2 years. After reconstitution, it is stable at 4°C for 1 week or -20°C for longer (with carrier protein). It is recommended to freeze aliquots at -20°C or -80°C for extended storage.

Room temperature in continental US; may vary elsewhere.