RAB5C, Human (HEK293, His)

IL5 Protein is a cytokine that plays a critical role in regulating immune responses, particularly in promoting the production and activation of eosinophils. It is involved in modulating allergic and inflammatory processes. Dysregulation of IL5 Protein has been associated with various diseases, including asthma and allergic rhinitis. Targeting IL5 Protein may offer potential therapeutic interventions in these conditions by inhibiting eosinophil activation and reducing inflammation. RAB5C, Human (HEK293, His) is the recombinant human-derived RAB5C, expressed by HEK293, with C-His labeled tag. The total length of RAB5C, Human (HEK293, His) is 216 a.a., with molecular weight of ~25 kDa.

RAB5C 是 Rab 蛋白家族的成员，是 Ras 超家族的一种小型 GTP 酶，被认为在确保囊泡对接和/或与其适当的受体区室融合的准确性方面发挥作用。它在多种组织中普遍表达，包括肾脏 (RPKM 55.2)、骨髓 (RPKM 47.2) 和 25 种其他组织。

Human

HEK293

C-His

NP_958842 (M1-N216)

5878

MAGRGGAARPNGPAAGNKICQFKLVLLGESAVGKSSLVLRFVKGQFHEYQESTIGAAFLTQTVCLDDTTVKFEIWDTAGQERYHSLAPMYYRGAQAAIVVYDITNTDTFARAKNWVKELQRQASPNIVIALAGNKADLASKRAVEFQEAQAYADDNSLLFMETSAKTAMNVNEIFMAIAKKLPKNEPQNATGAPGRNRGVDLQENNPASRSQCCSN

Approximately 25 kDa

• 
  Greater than 95% as determined by reducing SDS-PAGE.

无菌粉末

Lyophilized from a 0.22 μm filtered solution of PBS, pH 7.4.

<1 EU/μg, determined by LAL method.

It is not recommended to reconstitute to a concentration less than 100 μg/mL in ddH₂O. For long term storage it is recommended to add a carrier protein (0.1% BSA, 5% HSA, 10% FBS or 5% Trehalose).

Stored at -20°C for 2 years. After reconstitution, it is stable at 4°C for 1 week or -20°C for longer (with carrier protein). It is recommended to freeze aliquots at -20°C or -80°C for extended storage.

Room temperature in continental US; may vary elsewhere.