ROBO4 蛋白, Human (HEK293, His)

ROBO4 protein is a receptor for Slit proteins (especially SLIT2) and plays a crucial regulatory role in angiogenesis and blood vessel patterning. It mediates the inhibition of primary endothelial cell migration by Slit protein and helps regulate the angiogenic process. ROBO4 Protein, Human (HEK293, His) is the recombinant human-derived ROBO4 protein, expressed by HEK293 , with C-His labeled tag. The total length of ROBO4 Protein, Human (HEK293, His) is 422 a.a., with molecular weight of 55-65 kDa.

ROBO4 蛋白作为 Slit 蛋白（尤其是 SLIT2）的受体发挥作用，并且似乎在血管生成和血管模式形成中发挥着至关重要的作用。它涉及介导 Slit 蛋白对原代内皮细胞迁移的抑制，有助于调节血管生成过程中的细胞反应。此外，ROBO4 参与维持内皮屏障的组织和功能，其在内皮屏障组织和功能中的作用证明了这一点。该蛋白与 SLIT2 和 ENAH 相互作用，强调其在调节血管发育和内皮细胞行为中与关键配体和相关蛋白的特异性结合。

Human

HEK293

C-His

Q8WZ75 (Q48-E469)

54538  [NCBI]

55-65 kDa

Greater than 95% as determined by reducing SDS-PAGE

溶液

Supplied as a 0.2 μm filtered solution of PBS, pH 7.4.

<1 EU/μg, determined by LAL method.

N/A.

Stored at -80°C for 1 year. It is stable at -20°C for 3 months after opening. It is recommended to freeze aliquots at -80°C for extended storage. Avoid repeated freeze-thaw cycles.

Shipping with dry ice.