SCD 蛋白, Human (Cell-Free, His)

SCD proteins (or stearoyl-CoA desaturases) critically catalyze the introduction of the first double bond into saturated fatty acyl-CoA substrates (such as palmitoyl-CoA and stearoyl-CoA). This process produces a mixture of 16:1 and 18:1 unsaturated fatty acids, which play a crucial role in lipid biosynthesis. SCD Protein, Human (Cell-Free, His) is the recombinant human-derived SCD protein, expressed by E. coli Cell-free , with N-10*His labeled tag. The total length of SCD Protein, Human (Cell-Free, His) is 359 a.a., with molecular weight of 44.3 kDa.

SCD（硬脂酰辅酶 A 去饱和酶）是一种重要的酶，它利用 O(2) 和还原细胞色素 b5 的电子来催化将第一个双键引入饱和脂肪酰辅酶 A 底物，例如棕榈酰辅酶 A 和硬脂酰辅酶 A。该过程产生 16:1 和 18:1 不饱和脂肪酸的混合物，在脂质生物合成中发挥着至关重要的作用。SCD 在调节与脂肪生成和线粒体脂肪酸氧化相关的基因表达方面至关重要，有助于膜磷脂、胆固醇酯和甘油三酯的生物合成。此外，SCD 在维持身体能量稳态方面发挥着关键作用，凸显了其在基本细胞过程中的重要性。

Human

E. coli Cell-free

N-10*His

O00767 (M1-G359)

6319

MPAHLLQDDISSSYTTTTTITAPPSRVLQNGGDKLETMPLYLEDDIRPDIKDDIYDPTYKDKEGPSPKVEYVWRNIILMSLLHLGALYGITLIPTCKFYTWLWGVFYYFVSALGITAGAHRLWSHRSYKARLPLRLFLIIANTMAFQNDVYEWARDHRAHHKFSETHADPHNSRRGFFFSHVGWLLVRKHPAVKEKGSTLDLSDLEAEKLVMFQRRYYKPGLLMMCFILPTLVPWYFWGETFQNSVFVATFLRYAVVLNATWLVNSAAHLFGYRPYDKNISPRENILVSLGAVGEGFHNYHHSFPYDYSASEYRWHINFTTFFIDCMAALGLAYDRKKVSKAAILARIKRTGDGNYKSG

44.3 kDa

Greater than 90% as determined by reducing SDS-PAGE.

<1 EU/μg, determined by LAL method.