1. 重组蛋白
  2. Cytokines and Growth Factors
  3. SCF 蛋白, Mouse (P.pastoris)

SCF 蛋白, Mouse (P.pastoris)

目录号: HY-P7064
COA 产品使用指南

SCF 蛋白, Mouse (P.pastoris)是受体型蛋白酪氨酸激酶 KIT 的配体。在调节细胞存活和增殖,造血,干细胞维持,配子发生,肥大细胞发育,迁移和功能以及黑素生成中起重要作用。

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规格 价格 是否有货 数量
2 μg ¥770 In-stock
10 μg ¥1980 In-stock
50 μg ¥2980 In-stock
100 μg   询价  
250 μg   询价  

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描述

SCF Protein, Mouse (P.pastoris) is the ligand for the receptor-type protein-tyrosine kinase KIT. It plays an essential role in the regulation of cell survival and proliferation, hematopoiesis, stem cell maintenance, gametogenesis, mast cell development, migration and function, and in melanogenesis.

研究背景

Embryo implantation is a complex process that requires the interaction of embryo and endometrium. Several growth factors and cytokines appear to be involved in this process. Stem cell factor (SCF) and its receptor c-kit regulate the proliferation and survival of germ cells and play an important role in follicular development. During embryonic development, SCF and c-kit are essential for the survival and proliferation of the germ cell and migration toward the gonad. c-kit mRNA is expressed in the primordial germ cells, while the SCF transcript is expressed along their migratory pathway toward the genital ridge[1].

生物活性

The ED50 is <10.0 ng/mL as measured by human TF-1 cells, corresponding to a specific activity of >1.0× 105 units/mg.

种属

Mouse

表达系统

P. pastoris

标签

Tag Free

蛋白编号

P20826 (K26-A189)

基因 ID

17311  [NCBI]

同用名
rMuSCF; Hematopoietic growth factor KL; MGF; Mast Cell Growth Factor
氨基酸序列

MKEICGNPVTDNVKDITKLVANLPNDYMITLNYVAGMDVLPSHCWLRDMVIQLSLSLTTLLDKFSNISEGLSNYSIIDKLGKIVDDLVLCMEENAPKNIKESPKRPETRSFTPEEFFSIFNRSIDAFKDFMVASDTSDCVLSSTLGPEKDSRVSVTKPFMLPPVA

分子量

Approximately 18.4 kDa

性状

Lyophilized powder.

组分

Lyophilized after extensive dialysis against 50 mM Tris, pH 8.0.

内毒素含量

<0.2 EU/μg, determined by LAL method.

复溶方法

It is not recommended to reconstitute to a concentration less than 100 μg/mL in ddH2O.

保存条件 & 期限

Stored at -20°C. After reconstitution, it is stable at 4°C for 1 week or -20°C for longer. It is recommended to freeze aliquots at -20°C or -80°C for extended storage.

运输条件

Room temperature in continental US; may vary elsewhere.

文件资料
参考文献

SCF Protein, Mouse (P.pastoris) 相关分类

  • 复溶计算器

  • 重组蛋白稀释计算器

  • 比活力计算器

The reconstitution calculator equation

Volume (to add to vial) = Mass (in vial) ÷ Desired Reconstitution Concentration

Volume (to add to vial) = Mass (in vial) ÷ Desired Reconstitution Concentration
= ÷

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2

The specific active calculator equation

Specific Active (Unit/mg) = 106 ÷ Biological Activity (ED50)

Specific Active (Unit/mg) = 106 ÷ Biological Activity (ED50)
Unit/mg = 106 ÷ ng/mL

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产品名称:
SCF Protein, Mouse (P.pastoris)
目录号:
HY-P7064
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