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SCG3/Secretogranin-3 蛋白, Mouse (HEK293, His)

目录号: HY-P78352
产品使用指南

SCG3/Secretogranin-3 蛋白是颗粒蛋白家族的一员,在分泌颗粒的生物发生中发挥着关键的调节作用。作为嗜铬粒蛋白 A/CHGA 等颗粒内蛋白的分选受体,SCG3 有助于颗粒形成动力学。SCG3/Secretogranin-3 蛋白, Mouse (HEK293, His) 是重组的 SCG3/Secretogranin-3 蛋白,由 HEK293 表达,带有 C-His 标签。SCG3/Secretogranin-3 蛋白, Mouse (HEK293, His) 全长 449 个氨基酸,分子量为 60-70 kDa。

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描述

SCG3/Secretogranin-3 protein is a member of the granulin family and plays a critical regulatory role in the biogenesis of secretory granules. As a sorting receptor for intragranule proteins such as chromogranin A/CHGA, SCG3 contributes to granule formation dynamics. SCG3/Secretogranin-3 Protein, Mouse (HEK293, His) is the recombinant mouse-derived SCG3/Secretogranin-3 protein, expressed by HEK293 , with C-His labeled tag. The total length of SCG3/Secretogranin-3 Protein, Mouse (HEK293, His) is 449 a.a., with molecular weight of 60-70 kDa.

研究背景

SCG3/Secretogranin-3 蛋白是颗粒蛋白家族的一员,在调节分泌颗粒的生物发生中发挥着至关重要的作用。SCG3 作为颗粒内蛋白质(包括嗜铬粒蛋白 A/CHGA)的分选受体,有助于颗粒形成的动态过程。除了参与颗粒生物发生之外,SCG3 还可能在血管生成中发挥作用,通过 MEK/ERK 信号通路促进内皮增殖、迁移和管形成。该蛋白质与嗜铬粒蛋白 A (CHGA) 相互作用,突出了其与颗粒内蛋白质的关键关联。此外,SCG3 与促分泌素 II/SCG2 和羧肽酶 E (CPE) 相互作用,进一步强调其复杂地参与与颗粒动力学和血管生成相关的细胞过程。

种属

Mouse

表达系统

HEK293

标签

C-His

蛋白编号

P47867 (F23-L471)

基因 ID

20255  [NCBI]

蛋白结构
N-term
SCG3 (F23-L471)
Accession # P47867
His
C-term
同用名
Secretogranin-3; Secretogranin III; SCG3; SGIII; UNQ2502/PRO5990
分子量

60-70 kDa

纯度

Greater than 95% as determined by Tris-Bis PAGE.

内毒素含量

<1 EU/μg, determined by LAL method.

文件资料

SCG3/Secretogranin-3 Protein, Mouse (HEK293, His) 相关分类

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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The reconstitution calculator equation

Volume (to add to vial) = Mass (in vial) ÷ Desired Reconstitution Concentration

Volume (to add to vial) = Mass (in vial) ÷ Desired Reconstitution Concentration
= ÷

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2

The specific activity calculator equation

Specific Activity (Unit/mg) = 106 ÷ Biological Activity (ED50)

Specific Activity (Unit/mg) = 106 ÷ Biological Activity (ED50)
Unit/mg = 106 ÷ ng/mL

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产品名称:
SCG3/Secretogranin-3 Protein, Mouse (HEK293, His)
目录号:
HY-P78352
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