Semaphorin-3C/SEMA3C 蛋白, Human (HEK293, His)

Semaphorin-3C (SEMA3C) protein plays a crucial role in developmental processes by binding to plexin family members, particularly PLXND1, orchestrating intricate cellular signaling pathways. Its indispensable contribution to normal cardiovascular development during embryogenesis and its function as an attractant for growing axons underscore SEMA3C's significance in axon growth and guidance. Semaphorin-3C/SEMA3C Protein, Human (HEK293, His) is the recombinant human-derived Semaphorin-3C/SEMA3C protein, expressed by HEK293 , with C-6*His labeled tag. The total length of Semaphorin-3C/SEMA3C Protein, Human (HEK293, His) is 718 a.a., with molecular weight of 75-120 & 27 kDa, respectively.

Semaphorin-3C (SEMA3C) 蛋白通过与丛蛋白家族成员结合，充当发育过程中的关键调节因子。至关重要的是，SEMA3C 对于胚胎发生中的正常心血管发育是不可或缺的。其功能扩展到充当轴突生长的引诱剂，从而在轴突生长和引导中发挥重要作用。在分子相互作用中，SEMA3C 与 PLXND1 形成特定关联，突显其参与复杂的细胞信号传导途径，有助于协调发育事件。

Human

HEK293

C-6*His

Q99985 (G21-S738)

10512  [NCBI]

GSSQPQARVYLTFDELRETKTSEYFSLSHHPLDYRILLMDEDQDRIYVGSKDHILSLNINNISQEALSVFWPASTIKVEECKMAGKDPTHGCGNFVRVIQTFNRTHLYVCGSGAFSPVCTYLNRGRRSEDQVFMIDSKCESGKGRCSFNPNVNTVSVMINEELFSGMYIDFMGTDAAIFRSLTKRNAVRTDQHNSKWLSEPMFVDAHVIPDGTDPNDAKVYFFFKEKLTDNNRSTKQIHSMIARICPNDTGGLRSLVNKWTTFLKARLVCSVTDEDGPETHFDELEDVFLLETDNPRTTLVYGIFTTSSSVFKGSAVCVYHLSDIQTVFNGPFAHKEGPNHQLISYQGRIPYPRPGTCPGGAFTPNMRTTKEFPDDVVTFIRNHPLMYNSIYPIHKRPLIVRIGTDYKYTKIAVDRVNAADGRYHVLFLGTDRGTVQKVVVLPTNNSVSGELILEELEVFKNHAPITTMKISSKKQQLYVSSNEGVSQVSLHRCHIYGTACADCCLARDPYCAWDGHSCSRFYPTGKRRSRRQDVRHGNPLTQCRGFNLKAYRNAAEIVQYGVKNNTTFLECAPKSPQASIKWLLQKDKDRRKEVKLNERIIATSQGLLIRSVQGSDQGLYHCIATENSFKQTIAKINFKVLDSEMVAVVTDKWSPWTWASSVRALPFHPKDIMGAFSHSEMQMINQYCKDTRQQHQQGDESQKMRGDYGKLKALINS

75-120&27 kDa

Greater than 95% as determined by reducing SDS-PAGE.

溶液

Supplied as a 0.2 μm filter Solution of 20 mM NaH₂PO₄, 150 mM NaCl, 0.1 M Arginine, 0.1 M Glu, 10% Glycerol, 0.01% Tween20, 5% Trehalose, pH 7.4.

<1 EU/μg, determined by LAL method.

N/A.

Stored at -80°C for 1 year. It is stable at -20°C for 3 months after opening. It is recommended to freeze aliquots at -80°C for extended storage. Avoid repeated freeze-thaw cycles.

Shipping with dry ice.