SIRP gamma 蛋白, Human (HEK293, His-Avi)

SIRP gamma Protein, a probable immunoglobulin-like cell surface receptor, mediates cell-cell adhesion by binding with CD47. This interaction enhances antigen-specific T-cell proliferation and provides costimulatory signals for T-cell activation, highlighting SIRP gamma's role in modulating immune responses. The intricate interactions with CD47 underscore SIRP gamma's significance as a cell surface receptor, crucial in cellular adhesion and regulating T-cell activation pathways. SIRP gamma Protein, Human (HEK293, His-Avi) is the recombinant human-derived SIRP gamma protein, expressed by HEK293, with C-His, C-Avi labeled tag. The total length of SIRP gamma Protein, Human (HEK293, His-Avi) is 332 a.a., with molecular weight of 47-49 kDa.

SIRP γ 蛋白作为一种可能的免疫球蛋白样细胞表面受体出现，证明了其在与 CD47 结合后介导细胞间粘附的作用。这种相互作用对于增强抗原特异性 T 细胞增殖和为 T 细胞激活提供共刺激信号至关重要。结果，SIRP gamma 与抗原呈递细胞上的 CD47 结合，突出了它在调节免疫反应中的作用。SIRP gamma 和 CD47 之间复杂的相互作用强调了其作为细胞表面受体的重要性，在细胞粘附和 T 细胞激活途径的调节中发挥着至关重要的作用。

Human

HEK293

C-His;C-Avi

Q9P1W8 (E29-P360)

55423  [NCBI]

47-49 kDa

Greater than 95% as determined by Tris-Bis PAGE.

<1 EU/μg, determined by LAL method.