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SLAMF9 蛋白, Mouse (L224P, HEK293, His)

目录号: HY-P71005
产品使用指南

SLAM 家族成员 9 (Slamf9) 是信号淋巴细胞激活分子家族的成员。 Slamf9 是一种细胞表面分子,缺乏其他家族成员中发现的信号转导基序。 Slam9主要作为浆细胞样树突状细胞(pDC)受体,对于pDC的分化、功能和维持至关重要,并且还参与炎症的引发和细菌感染的清除。SLAMF9 蛋白, Mouse (L224P, HEK293, His) 是重组的 SLAMF9 蛋白,由 HEK293 表达,带有 C-6*His 标签和 L224P 突变。SLAMF9 蛋白, Mouse (L224P, HEK293, His) 全长 213 个氨基酸,分子量为 30-80 kDa。

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描述

SLAM family member 9 (Slamf9) is a member of the signaling lymphocytic activation molecule family. Slamf9 is a cell surface molecule that lacks the signal transduction motifs found in other family members. Slam9 acts mainly as a plasmacytoid dendritic cell (pDC) receptor and is essential for differentiation, function and maintenance of pDCs, and is also involved in the initiation of inflammation and clearance of bacterial infection. SLAMF9 Protein, Mouse (L224P, HEK293, His) is the recombinant mouse-derived SLAMF9 protein, expressed by HEK293 , with C-6*His labeled tag and L224P mutation. The total length of SLAMF9 Protein, Mouse (L224P, HEK293, His) is 213 a.a., with molecular weight of 30-80 kDa.

研究背景

SLAM 家族成员 9 (Slamf9) 是信号淋巴细胞激活分子家族的成员。 Slamf9 是一种细胞表面分子,由两个胞外免疫球蛋白结构域、一个跨膜结构域和一个短胞质尾组成,该尾部缺乏其他家族成员中发现的信号转导基序。 Slam9 是一种浆细胞样树突状细胞 (pDC) 受体,对于 pDC 的分化至关重要,可调节 pDC 在健康和炎症期间的功能和维持。 SLAMF9 还参与炎症的引发和细菌感染的清除[1][2][3]

种属

Mouse

表达系统

HEK293

标签

C-6*His

蛋白编号

BAB26328.1 (F18-L230, L224P)

基因 ID

98365  [NCBI]

蛋白结构
N-term
SLAMF9 (F18-L230, L224P)
Accession # BAB26328.1
6*His
C-term
同用名
SLAM family member 9; Slamf9
氨基酸序列

FSGDDEDPEEVVGVLQESINLSLEIPSNEEIKHIDWLFQNNIAIVKPGKKGQPAVIMAVDPRYRGRVSISESSYSLHISNLTWEDSGLYNAQVNLKTSESHITKSYHLRVYRRLSKPHITVNSNISEEGVCNISLTCSIERAGMDVTYIWLSSQDSTNTSHEGSVLSTSWRPGDKAPSYTCRVSNPISNISSRRISVGSFCADPGYPEKPSML

分子量

30-80 kDa

纯度

Greater than 95% as determined by reducing SDS-PAGE.

内毒素含量

<1 EU/μg, determined by LAL method.

文件资料

SLAMF9 Protein, Mouse (L224P, HEK293, His) 相关分类

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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The reconstitution calculator equation

Volume (to add to vial) = Mass (in vial) ÷ Desired Reconstitution Concentration

Volume (to add to vial) = Mass (in vial) ÷ Desired Reconstitution Concentration
= ÷

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2

The specific activity calculator equation

Specific Activity (Unit/mg) = 106 ÷ Biological Activity (ED50)

Specific Activity (Unit/mg) = 106 ÷ Biological Activity (ED50)
Unit/mg = 106 ÷ ng/mL

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SLAMF9 Protein, Mouse (L224P, HEK293, His)
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HY-P71005
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