SULT1A3 蛋白, Human (His)

SULT1A3 protein, a sulfotransferase utilizing PAPS, catalyzes the sulfate conjugation of phenolic monoamines, including neurotransmitters (dopamine, norepinephrine, serotonin) and drugs. This activity contributes significantly to inactivation and elimination, emphasizing SULT1A3's crucial role in regulating neurotransmitter and drug levels, maintaining homeostasis, and ensuring proper biological system functioning. SULT1A3 Protein, Human (His) is the recombinant human-derived SULT1A3 protein, expressed by E. coli , with N-6*His labeled tag. The total length of SULT1A3 Protein, Human (His) is 295 a.a., with molecular weight of ~35.0 kDa.

SULT1A3 蛋白是一种利用 3'-磷酸-5'-腺苷基硫酸盐 (PAPS) 作为磺酸盐供体的磺基转移酶，在催化酚类单胺（包括多巴胺、去甲肾上腺素和血清素等神经递质）的硫酸盐结合中发挥着关键作用如酚类和儿茶酚类药物。这种酶活性对这些生物活性分子的失活和消除有显着贡献，凸显了 SULT1A3 在调节神经递质和某些药理学相关化合物的水平和活性方面的关键作用。SULT1A3 的底物特异性强调了其在调节对神经递质和药物的生理反应中的重要性，强调了其在维持生物系统的稳态和正常功能方面的重要性。

The enzyme activity of this recombinant protein is testing in progress, we cannot offer a guarantee yet.

Human

E. coli

N-6*His

P0DMM9 (M1-L295)

445329  [NCBI]

MELIQDTSRPPLEYVKGVPLIKYFAEALGPLQSFQARPDDLLINTYPKSGTTWVSQILDMIYQGGDLEKCNRAPIYVRVPFLEVNDPGEPSGLETLKDTPPPRLIKSHLPLALLPQTLLDQKVKVVYVARNPKDVAVSYYHFHRMEKAHPEPGTWDSFLEKFMAGEVSYGSWYQHVQEWWELSRTHPVLYLFYEDMKENPKREIQKILEFVGRSLPEETMDFMVQHTSFKEMKKNPMTNYTTVPQELMDHSISPFMRKGMAGDWKTTFTVAQNERFDADYAEKMAGCSLSFRSEL

Approximately 35.0 kDa

Greater than 95% as determined by reducing SDS-PAGE.

溶液

Supplied as a 0.2 μm filtered solution of 20 mM Tris-HCl, 100 mM NaCl, pH 8.0.

<1 EU/μg, determined by LAL method.

Stored at -80°C for 1 year. It is stable at -20°C for 3 months after opening. It is recommended to freeze aliquots at -80°C for extended storage. Avoid repeated freeze-thaw cycles.

Shipping with dry ice.