SWSAP1 蛋白, Human (His)

SWSAP1, an ATPase selectively activated by single-stranded DNA, is vital for homologous recombination repair (HRR). In addition to ATPase activity, SWSAP1 independently binds DNA. Teaming up with ZSWIM7, it forms a complex crucial for HRR, with mutual stabilization. SWSAP1 interacts with key HRR proteins—RAD51, RAD51B, RAD51C, RAD51D, and XRCC3—underscoring its role in facilitating homologous recombination repair processes. SWSAP1 Protein, Human (His) is the recombinant human-derived SWSAP1 protein, expressed by E. coli , with N-6*His labeled tag.

ATPase SWSAP1 受到单链 DNA 的选择性刺激，在同源重组修复 (HRR) 中发挥着至关重要的作用。除了 ATP 酶活性外，SWSAP1 还表现出独立的 DNA 结合能力。它与 ZSWIM7 形成功能复合物，有助于同源重组修复，并且两种蛋白质相互稳定。SWSAP1 进一步与 HRR 中涉及的关键蛋白相互作用，包括 RAD51、RAD51B、RAD51C、RAD51D 和 XRCC3，突出显示其参与促进同源重组修复过程。

Human

E. coli

N-6*His

Q6NVH7 (M1-P229)

126074  [NCBI]

Full Length

MPAAGPPLLLLGTPGSGKTALLFAAALEAAGEGQGPVLFLTRRPLQSMPRGTGTTLDPMRLQKIRFQYPPSTRELFRLLCSAHEAPGPAPSLLLLDGLEEYLAEDPEPQEAAYLIALLLDTAAHFSHRLGPGRDCGLMVALQTQEEAGSGDVLHLALLQRYFPAQCWLQPDAPGPGEHGLRACLEPGGLGPRTEWWVTFRSDGEMMIAPWPTQAGDPSSGKGSSSGGQP

Approximately 30.0 kDa

Greater than 95% as determined by reducing SDS-PAGE.

溶液.

Supplied as a 0.22 μm filtered solution of PBS, 1 mM EDTA, pH 7.4.

<1 EU/μg, determined by LAL method.

N/A.

Stored at -80°C for 1 year from date of receipt. It is stable at -20°C for 3 months after opening. It is recommended to freeze aliquots at -80°C for extended storage. Avoid repeated freeze-thaw cycles.

Shipping with dry ice.