TINAGL1 蛋白, Human (HEK293, His)

TINAGL1 Protein, implicated in adrenocortical zonation, may regulate distinct adrenal cortex zones and repress CYP11B1 gene expression in adrenocortical cells. As a member of the non-catalytic peptidase C1 family, its distinctive function does not involve enzymatic activity. Unraveling TINAGL1's molecular pathways could offer insights into its role in adrenal physiology, shedding light on its potential to manipulate adrenal function. TINAGL1 Protein, Human (HEK293, His) is the recombinant human-derived TINAGL1 protein, expressed by HEK293 , with C-6*His labeled tag. The total length of TINAGL1 Protein, Human (HEK293, His) is 446 a.a., with molecular weight of 55-60 kDa.

TINAGL1 蛋白作为肾上腺皮质分区中的潜在参与者而出现，表明它参与了肾上腺皮质内不同区域的复杂调节。此外，它可能参与抑制肾上腺皮质细胞中 CYP11B1 基因表达的机制，表明其在调节与肾上腺功能相关的关键基因中发挥作用。值得注意的是，TINAGL1 属于非催化肽酶 C1 家族，表明其具有不涉及酶活性的独特功能。解开 TINAGL1 影响肾上腺皮质分区和基因表达的特定分子途径，可以为其在肾上腺生理学中的作用提供有价值的见解，并可能为理解和操纵肾上腺功能开辟途径。

Human

HEK293

C-6*His

Q9GZM7 (A22-H467)

64129  [NCBI]

AQQGRGRRELAPGLHLRGIRDAGGRYCQEQDLCCRGRADDCALPYLGAICYCDLFCNRTVSDCCPDFWDFCLGVPPPFPPIQGCMHGGRIYPVLGTYWDNCNRCTCQENRQWQCDQEPCLVDPDMIKAINQGNYGWQAGNHSAFWGMTLDEGIRYRLGTIRPSSSVMNMHEIYTVLNPGEVLPTAFEASEKWPNLIHEPLDQGNCAGSWAFSTAAVASDRVSIHSLGHMTPVLSPQNLLSCDTHQQQGCRGGRLDGAWWFLRRRGVVSDHCYPFSGRERDEAGPAPPCMMHSRAMGRGKRQATAHCPNSYVNNNDIYQVTPVYRLGSNDKEIMKELMENGPVQALMEVHEDFFLYKGGIYSHTPVSLGRPERYRRHGTHSVKITGWGEETLPDGRTLKYWTAANSWGPAWGERGHFRIVRGVNECDIESFVLGVWGRVGMEDMGHH

55-60 kD

Greater than 95% as determined by reducing SDS-PAGE.

溶液.

Supplied as a 0.2 μm filtered solution of 20 mM Tris-HCl, 150 mM NaCl, 10% Glycerol, 0.05% Brij35, pH 7.5.

<1 EU/μg, determined by LAL method.

Stored at -80°C for 1 year. It is stable at -20°C for 3 months after opening. It is recommended to freeze aliquots at -80°C for extended storage. Avoid repeated freeze-thaw cycles.

Shipping with dry ice.