2. 重组蛋白
  3. Cytokines and Growth Factors
  4. TNF Superfamily
  5. TNF Receptor Superfamily
  6. Decoy Receptor 1
  7. TNFRSF10C 蛋白, Human (210a.a, HEK293, His)

TNFRSF10C 蛋白, Human (210a.a, HEK293, His)

目录号: HY-P76860
产品使用指南

TNFRSF10C 蛋白是 TRAIL 的一种受体，缺乏细胞质死亡结构域，使其无法诱导细胞凋亡。相反，它可以通过与 TRAIL-R1 和 R2 竞争配体结合来保护细胞，充当诱饵受体并减轻 TRAIL 介导的细胞凋亡。这一独特的功能强调了 TNFRSF10C 在调节细胞对 TRAIL 信号传导反应方面的调控复杂性，表明它参与微调生存和凋亡途径之间的平衡。TNFRSF10C 蛋白, Human (210a.a, HEK293, His) 是重组的 TNFRSF10C 蛋白，由 HEK293 表达，带有 C-His 标签。TNFRSF10C 蛋白, Human (210a.a, HEK293, His) 全长 210 个氨基酸，分子量约为 ~23.6 KDa。

MCE 的所有产品仅用作科学研究或药证申报，我们不为任何个人用途提供产品和服务

重组蛋白定制服务

1.  客户无需承担相应的运输费用。

2.  同一机构（单位）同一产品试用装仅限申领一次，同一机构（单位）一年内

     可免费申领三个不同产品的试用装。

3.  试用装只面向终端客户。

规格 是否有货
50 μg   询价  
100 μg   询价  

* Please select Quantity before adding items.

Top Publications Citing Use of Products

  • 生物活性

  • 技术参数

  • 产品性质

  • 产品资料

描述

TNFRSF10C Protein, a receptor for TRAIL, lacks a cytoplasmic death domain, making it unable to induce apoptosis. Instead, it may protect cells by competing with TRAIL-R1 and R2 for ligand binding, acting as a decoy receptor and mitigating TRAIL-mediated apoptosis. This unique feature underscores TNFRSF10C's regulatory complexity in modulating cellular responses to TRAIL signaling, suggesting its involvement in fine-tuning the balance between survival and apoptotic pathways. TNFRSF10C Protein, Human (210a.a, HEK293, His) is the recombinant human-derived TNFRSF10C protein, expressed by HEK293, with C-His labeled tag. The total length of TNFRSF10C Protein, Human (210a.a, HEK293, His) is 210 a.a., with molecular weight of ~23.6 KDa.
研究背景

TNFRSF10C 蛋白作为细胞毒性配体 TRAIL 的受体；然而，它缺乏细胞质死亡结构域，使其无法诱导细胞凋亡。相反，TNFRSF10C 可能通过与 TRAIL-R1 和 R2 竞争与配体的结合，在细胞中发挥保护作用，可能充当诱饵受体，从而减轻 TRAIL 介导的细胞凋亡。这一独特的特征凸显了 TNFRSF10C 在调节细胞对 TRAIL 信号反应的反应中的调节复杂性，并表明它参与微调生存和凋亡途径之间的平衡。
种属

Human
表达系统

HEK293
标签

C-His
蛋白编号

O14798 (A26-P235)
基因 ID
蛋白结构
N-term
TNFRSF10C (A26-P235)
Accession # O14798
His
C-term
同用名
Tumor necrosis factor receptor superfamily member 10C; DcR1; TRAIL-R3; CD263
分子量

Approximately 23.6 kDa.
纯度

Greater than 95% as determined by reducing SDS-PAGE.
内毒素含量

<1 EU/μg, determined by LAL method.
文件资料
产品使用指南 (1213 KB)

TNFRSF10C Protein, Human (210a.a, HEK293, His) 相关分类

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

  • 复溶计算器

  • 重组蛋白稀释计算器

  • 比活力计算器

The reconstitution calculator equation

Volume (to add to vial) = Mass (in vial) ÷ Desired Reconstitution Concentration

Volume (to add to vial) = Mass (in vial) ÷ Desired Reconstitution Concentration
= ÷

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2

The specific activity calculator equation

Specific Activity (Unit/mg) = 106 ÷ Biological Activity (ED50)

Specific Activity (Unit/mg) = 106 ÷ Biological Activity (ED50)
Unit/mg = 106 ÷ ng/mL

您最近查看的产品:

Your information is safe with us. * Required Fields.

   产品名称：

  

* 需求量：

* 客户姓名：

 

* Email：

* 电话：

 

* 公司或机构名称：

   留言给我们：

Bulk Inquiry

Inquiry Information

产品名称：
TNFRSF10C Protein, Human (210a.a, HEK293, His)
目录号：
HY-P76860
需求量：

Request for HNMR Report

Please fill out this form to request the QC report. We will send it to your Email address shortly.

Your information is safe with us. * Required Fields.

   产品名称：

  

* Lot #：

* 客户姓名：

 

* Email：

* 电话：

 

* 公司或机构名称：

   留言给我们：

Request for HNMR Report

We have received your request and will respond to you as soon as possible.

嗨！很高兴为您提供帮助！

尊敬的 MCE 客户您好，
请您选择所在区域，我们将转接对应客服为您服务！

热门区域

A

B

C

F

G

H

J

L

N

Q

S

T

X

Y

Z

热 A B C F G H J L N Q S T X Y Z