Transferrin 蛋白, Mouse (HEK293, His)

Transferrin is an important iron-binding transport protein that combines two Fe(3+) ions with an anion, usually bicarbonate. Its main function is to transport iron from the site of absorption to the site of storage and utilization. Transferrin Protein, Mouse (HEK293, His) is the recombinant mouse-derived Transferrin protein, expressed by HEK293 , with C-10*His labeled tag. The total length of Transferrin Protein, Mouse (HEK293, His) is 678 a.a., with molecular weight of approximately 85 kDa.

转铁蛋白是一种关键的铁结合转运蛋白，具有结合两个 Fe(3+) 离子和一个阴离子（通常是碳酸氢根）的能力。它的主要职责在于促进铁从吸收位点和血红素降解运输到指定的体内储存和利用位置。除了在铁稳态中的基本作用之外，血清转铁蛋白还可能在促进细胞增殖方面发挥作用。转铁蛋白的结构为单体，其多方面功能强调了其在协调铁分布和细胞过程的复杂平衡方面的重要性，这对于整体生理健康至关重要。

Measured in a cell proliferation assay using A549 human non small cell lung cancer cell. The ED₅₀ for this effect is 187.3 ng/mL, corresponding to a specific activity is 5339.028 U/mg.

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  Measured in a cell proliferation assay using A549 human non small cell lung cancer cell. The ED₅₀ for this effect is 187.3 ng/mL, corresponding to a specific activity is 5339.028 U/mg.

Mouse

HEK293

C-10*His

Q921I1 (V20-H697)

22041  [NCBI]

VPDKTVKWCAVSEHENTKCISFRDHMKTVLPPDGPRLACVKKTSYPDCIKAISASEADAMTLDGGWVYDAGLTPNNLKPVAAEFYGSVEHPQTYYYAVAVVKKGTDFQLNQLEGKKSCHTGLGRSAGWVIPIGLLFCKLSEPRSPLEKAVSSFFSGSCVPCADPVAFPKLCQLCPGCGCSSTQPFFGYVGAFKCLKDGGGDVAFVKHTTIFEVLPEKADRDQYELLCLDNTRKPVDQYEDCYLARIPSHAVVARKNNGKEDLIWEILKVAQEHFGKGKSKDFQLFSSPLGKDLLFKDSAFGLLRVPPRMDYRLYLGHNYVTAIRNQQEGVCPEGSIDNSPVKWCALSHLERTKCDEWSIISEGKIECESAETTEDCIEKIVNGEADAMTLDGGHAYIAGQCGLVPVMAEYYESSNCAIPSQQGIFPKGYYAVAVVKASDTSITWNNLKGKKSCHTGVDRTAGWNIPMGMLYNRINHCKFDEFFSQGCAPGYEKNSTLCDLCIGPLKCAPNNKEEYNGYTGAFRCLVEKGDVAFVKHQTVLDNTEGKNPAEWAKNLKQEDFELLCPDGTRKPVKDFASCHLAQAPNHVVVSRKEKAARVKAVLTSQETLFGGSDCTGNFCLFKSTTKDLLFRDDTKCFVKLPEGTTPEKYLGAEYMQSVGNMRKCSTSRLLEACTFHKH

approximately 85 kDa

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  Greater than 95% as determined by reducing SDS-PAGE.

无菌粉末.

Lyophilized from a 0.2 μm filtered solution of PBS, pH 7.4

<1 EU/μg, determined by LAL method.

It is not recommended to reconstitute to a concentration less than 100 μg/mL in ddH₂O. For long term storage it is recommended to add a carrier protein (0.1% BSA, 5% HSA, 10% FBS or 5% Trehalose).

Stored at -20°C for 2 years. After reconstitution, it is stable at 4°C for 1 week or -20°C for longer (with carrier protein). It is recommended to freeze aliquots at -20°C or -80°C for extended storage.

Room temperature in continental US; may vary elsewhere.