2. 重组蛋白
  3. CD Antigens
  4. Macrophage CD Proteins Monocyte CD Proteins Dendritic Cell CD Proteins
  5. TREM-1/CD354
  6. TREM-1 蛋白, Cynomolgus (HEK293, His)

TREM-1 蛋白, Cynomolgus (HEK293, His)

目录号: HY-P77860
产品使用指南

TREM-1 蛋白是一种细胞表面受体，通过增强炎症反应来严格调节先天性和适应性免疫。TREM-1 在急性和慢性炎症性疾病中发挥着至关重要的作用，充当诱饵受体来平衡其促炎作用。TREM-1 蛋白, Cynomolgus (HEK293, His) 是重组的 TREM-1 蛋白，由 HEK293 表达，带有 C-His 标签。TREM-1 蛋白, Cynomolgus (HEK293, His) 全长 181 个氨基酸，分子量为 45-60 kDa。

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描述

The TREM-1 protein is a cell surface receptor that critically regulates innate and adaptive immunity by enhancing inflammatory responses. TREM-1 plays a crucial role in acute and chronic inflammatory diseases, acting as a decoy receptor to balance its pro-inflammatory effects. TREM-1 Protein, Cynomolgus (HEK293, His) is the recombinant cynomolgus-derived TREM-1 protein, expressed by HEK293 , with C-His labeled tag. The total length of TREM-1 Protein, Cynomolgus (HEK293, His) is 181 a.a., with molecular weight of 45-60 kDa.
研究背景

TREM-1 蛋白作为细胞表面受体，可能参与先天性和适应性免疫反应。磷酸化后，它与 PTPN6 和 PTPN11 相互作用，表明它在与这些磷酸酶相关的信号通路中的作用。这种相互作用凸显了 TREM-1 可能有助于调节免疫系统的调节机制。
种属

Cynomolgus
表达系统

HEK293
标签

C-His
蛋白编号

XP_005553111 (T21-P201)
基因 ID

102129811  [NCBI]
蛋白结构
N-term
TREM-1 (T21-P201)
Accession # XP_005553111
His
C-term
同用名
CD354; TREM-1
分子量

45-60 kDa
纯度

Greater than 95% as determined by Tris-Bis PAGE.
内毒素含量

<1 EU/μg, determined by LAL method.
文件资料
产品使用指南 (1213 KB)

TREM-1 Protein, Cynomolgus (HEK293, His) 相关分类

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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The reconstitution calculator equation

Volume (to add to vial) = Mass (in vial) ÷ Desired Reconstitution Concentration

Volume (to add to vial) = Mass (in vial) ÷ Desired Reconstitution Concentration
= ÷

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2

The specific activity calculator equation

Specific Activity (Unit/mg) = 106 ÷ Biological Activity (ED50)

Specific Activity (Unit/mg) = 106 ÷ Biological Activity (ED50)
Unit/mg = 106 ÷ ng/mL

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