1. 重组蛋白
  2. Cytokines and Growth Factors
  3. VEGF & VEGFR
  4. VEGF
  5. VEGF-D
  6. VEGF-D 蛋白, Human (117a.a, HEK293, His)

VEGF-D 蛋白, Human (117a.a, HEK293, His)

目录号: HY-P703960
产品使用指南 技术支持

VEGF-DD蛋白是血管生成、淋巴管生成和内皮细胞生长中的有效生长因子,在刺激细胞增殖、迁移和影响血管通透性方面发挥关键作用。它可能参与胚胎发生过程中静脉和淋巴管系统的形成,表明它在血管发育中起着关键作用。VEGF-D 蛋白, Human (117a.a, HEK293, His) 是重组的 VEGF-D 蛋白,由 HEK293 表达,带有 C-His 标签。

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描述

VEGF-DD protein is a potent growth factor in angiogenesis, lymphangiogenesis, and endothelial cell growth, playing a key role in stimulating cell proliferation, migration, and affecting vascular permeability. It may be involved in the formation of veins and lymphatic vasculature during embryogenesis, suggesting that it plays a key role in vascular development. VEGF-D Protein, Human (117a.a, HEK293, His) is the recombinant human-derived VEGF-D protein, expressed by HEK293, with C-His labeled tag.

研究背景

VEGF-DD 蛋白是一种在血管生成、淋巴管生成和内皮细胞生长中具有显着活性的生长因子,在刺激这些细胞的增殖和迁移方面发挥着关键作用,同时也影响血管通透性。它在胚胎发生过程中可能参与静脉和淋巴管系统的形成,这表明它在血管发育中发挥着关键作用。此外,VEGF-DD 可能有助于维持成人分化的淋巴内皮。该蛋白通过结合和激活 VEGFR-2 (KDR/FLK1) 和 VEGFR-3 (FLT4) 受体来实现这些效果。在结构上,VEGF-DD 以同二聚体形式存在,表现出非共价和反平行排列,突出了其在调节血管过程中的多方面作用,并强调了其在发育和成人血管生成和淋巴管生成中的重要性。

种属

Human

表达系统

HEK293

标签

C-8*His

蛋白编号

O43915 (F89-R205)

基因 ID

2277

蛋白结构
N-term
VEGF-DD (F89-R205)
Accession # O43915
8*His
C-term
蛋白长度

Partial

中文名
血管内皮生长因子-DD 蛋白
同用名
FIGF; VEGFD
预测分子量
14.7 kDa
分子量

Approximately 23-43 kDa,based on SDS-PAGE under reducing conditions,due to the glycosylation.

纯度

Greater than 95% as determined by Tris-Bis PAGE.

内毒素含量

<1 EU/μg, determined by LAL method.

文件资料

VEGF-D Protein, Human (117a.a, HEK293, His) 相关分类

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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The reconstitution calculator equation

Volume (to add to vial) = Mass (in vial) ÷ Desired Reconstitution Concentration

Volume (to add to vial) = Mass (in vial) ÷ Desired Reconstitution Concentration
= ÷

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2

The specific activity calculator equation

Specific Activity (Unit/mg) = 106 ÷ Biological Activity (ED50)

Specific Activity (Unit/mg) = 106 ÷ Biological Activity (ED50)
Unit/mg = 106 ÷ ng/mL

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产品名称:
VEGF-D Protein, Human (117a.a, HEK293, His)
目录号:
HY-P703960
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