VEGF145 蛋白, Human (HEK293, solution)

VEGF145 Protein is a subtype of Vascular Endothelial Growth Factor A (VEGF-A). VEGF-A is a key member of the VEGF family of cytokines that can promote neovascularization and increase vascular permeability. VEGF145 Protein, Human (HEK293) is the recombinant human-derived VEGF145 protein, expressed by HEK293 , with tag free. The total length of VEGF145 Protein, Human (HEK293) is 145 a.a., with molecular weight of ~16.92 kDa.

VEGF145 是血管内皮生长因子 A (VEGF-A) 的一个亚型。VEGF-A 是一种在血管生成、血管形成和内皮细胞生长中活跃的生长因子。VEGF-A 诱导内皮细胞增殖、促进细胞迁移、抑制细胞凋亡并诱导血管通透化。VEGF-A 与 FLT1/VEGFR1 和 KDR/VEGFR2 受体以及硫酸肝素和肝素结合。它还与 NRP1/神经纤毛蛋白-1 受体结合。当 VEGF-A 与 NRP1 结合时，它会启动运动神经元轴突引导和细胞体迁移所需的信号通路，包括面部运动神经元在胚胎发育过程中从菱脑节 4 向菱脑节 6 的尾部迁移。此外，VEGF-A 还与 DEAR/FBXW7-AS1 受体结合。

Human

HEK293

Tag Free

P15692-6 (A27-R171)

7422  [NCBI]

Partial

APMAEGGGQNHHEVVKFMDVYQRSYCHPIETLVDIFQEYPDEIEYIFKPSCVPLMRCGGCCNDEGLECVPTEESNITMQIMRIKPHQGQHIGEMSFLQHNKCECRPKKDRARQEKKSVRGKGKGQKRKRKKSRYKSWSVCDKPRR

Approximately 19-23 kDa, due to the glycosylation.

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  Greater than 95% as determined by reducing SDS-PAGE.

溶液

Supplied as a 0.22 μm filtered solution of PBS, pH 7.4.

<1 EU/μg, determined by LAL method.

N/A.

Stored at -80°C for 1 year from date of receipt. It is stable at -20°C for 3 months after opening. It is recommended to freeze aliquots at -80°C for extended storage. Avoid repeated freeze-thaw cycles.

Shipping with dry ice.