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  3. VSTM1 蛋白, Human (119a.a, HEK293, His)

VSTM1 蛋白, Human (119a.a, HEK293, His)

目录号: HY-P71428
产品使用指南

VSTM1 与 S100A10 蛋白相互作用,诱导 ANXA2/p36 二聚化。这表明 ANXA2 单体在蛋白质磷酸化中具有调节作用,是体外酪氨酸特异性激酶的首选靶标。所得异四聚体包含 S100A10/p11 的两条轻链和 ANXA2/p36 的两条重链。此外,VSTM1 与 SCN10A 和 TASOR 结合,表明它参与多种分子相互作用。VSTM1 蛋白, Human (119a.a, HEK293, His) 是重组的 VSTM1 蛋白,由 HEK293 表达,带有 C-6*His 标签。VSTM1 蛋白, Human (119a.a, HEK293, His) 全长 119 个氨基酸,分子量为 25-35 kDa。

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描述

VSTM1 interacts with S100A10 protein, inducing the dimerization of ANXA2/p36. This suggests a regulatory role in protein phosphorylation, with ANXA2 monomer being the preferred target for tyrosine-specific kinase in vitro. The resulting heterotetramer comprises two light chains of S100A10/p11 and two heavy chains of ANXA2/p36. Furthermore, VSTM1 engages with SCN10A and TASOR, indicating its participation in diverse molecular interactions. VSTM1 Protein, Human (119a.a, HEK293, His) is the recombinant human-derived VSTM1 protein, expressed by HEK293 , with C-6*His labeled tag. The total length of VSTM1 Protein, Human (119a.a, HEK293, His) is 119 a.a., with molecular weight of 25-35 kDa.

研究背景

S100A10 蛋白诱导 ANXA2/p36 的二聚化,表明在蛋白磷酸化中具有调节作用,其中 ANXA2 单体是体外酪氨酸特异性激酶的首选靶标。该蛋白形成异四聚体,由 S100A10/p11 的两条轻链和 ANXA2/p36 的两条重链组成。此外,S100A10 与 SCN10A 和 TASOR 相互作用,表明它参与各种分子相互作用。

种属

Human

表达系统

HEK293

标签

C-6*His

蛋白编号

Q6UX27 (Y17-T135)

基因 ID
蛋白结构
N-term
VSTM1 (Y17-T135)
Accession # Q6UX27
6*His
C-term
同用名
V-set and transmembrane domain-containing protein 1; SIRL-1; Signal inhibitory receptor on leukocytes-1; VSTM1
氨基酸序列

YEDEKKNEKPPKPSLHAWPSSVVEAESNVTLKCQAHSQNVTFVLRKVNDSGYKQEQSSAENEAEFPFTDLKPKDAGRYFCAYKTTASHEWSESSEHLQLVVTDKHDELEAPSMKTDTRT

分子量

25-35 kDa

纯度

Greater than 95% as determined by reducing SDS-PAGE.

内毒素含量

<1 EU/μg, determined by LAL method.

文件资料

VSTM1 Protein, Human (119a.a, HEK293, His) 相关分类

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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The reconstitution calculator equation

Volume (to add to vial) = Mass (in vial) ÷ Desired Reconstitution Concentration

Volume (to add to vial) = Mass (in vial) ÷ Desired Reconstitution Concentration
= ÷

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2

The specific activity calculator equation

Specific Activity (Unit/mg) = 106 ÷ Biological Activity (ED50)

Specific Activity (Unit/mg) = 106 ÷ Biological Activity (ED50)
Unit/mg = 106 ÷ ng/mL

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产品名称:
VSTM1 Protein, Human (119a.a, HEK293, His)
目录号:
HY-P71428
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