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  3. VSTM5 蛋白, Human (His)

VSTM5 蛋白, Human (His)

目录号: HY-P71443
产品使用指南

VSTM5 蛋白在中枢神经系统 (CNS) 中充当细胞粘附样膜蛋白,通过调节中枢神经元的膜形态和动力学,对中枢神经元的定位和复杂性产生关键影响。它积极参与神经元树突和突起(包括树突丝状伪足)的形成,有助于神经网络的复杂结构。VSTM5 蛋白, Human (His) 是重组的 VSTM5 蛋白,由 E. coli 表达,带有 N-His 标签。VSTM5 蛋白, Human (His) 全长 119 个氨基酸,分子量约为 ~19.3 kDa。

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描述

The VSTM5 protein acts as a cell adhesion-like membrane protein in the central nervous system (CNS) and exerts a critical influence on the positioning and complexity of central neurons by regulating their membrane morphology and dynamics. It is actively involved in the formation of neuronal dendrites and protrusions, including dendritic filopodia, contributing to the complex structure of neural networks. VSTM5 Protein, Human (His) is the recombinant human-derived VSTM5 protein, expressed by E. coli , with N-His labeled tag. The total length of VSTM5 Protein, Human (His) is 119 a.a., with molecular weight of ~19.3 kDa.

研究背景

VSTM5 是一种主要存在于中枢神经系统 (CNS) 中的细胞粘附样膜蛋白,通过改变中枢神经元的膜形态和动力学,对中枢神经元的定位和复杂性产生重大影响。从功能上讲,VSTM5 参与神经元树突和突起(包括树突丝状伪足)的形成,并通过改变树突棘形态和肌动蛋白分布来调节突触形成,从而在突触发生中发挥关键作用。值得注意的是,它促进不稳定神经元棘的形成,特别是细的和分支的类型。在大脑皮层发育过程中,VSTM5 在神经元形态发生和迁移中发挥调节作用。此外,VSTM5 表现出通过同一细胞膜内的顺式相互作用进行同源寡聚化的能力。

种属

Human

表达系统

E. coli

标签

N-His

蛋白编号

A8MXK1 (29L-147H)

基因 ID

387804  [NCBI]

蛋白结构
N-term
His
VSTM5 (29L-147H)
Accession # A8MXK1
C-term
同用名
Chromosome 11 open reading frame 90; CK090 HUMAN; Uncharacterized protein C11orf90; V set and transmembrane domain containing 5; V-set and transmembrane domain-containing protein 5
氨基酸序列

LQSQGVSLYIPQATINATVKEDILLSVEYSCHGVPTIEWTYSSNWGTQKIVEWKPGTQANISQSHKDRVCTFDNGSIQLFSVGVRDSGYYVITVTERLGSSQFGTIVLHVSEILYEDLH

分子量

Approximately 19.3 kDa

纯度

Greater than 90% as determined by reducing SDS-PAGE.

内毒素含量

<1 EU/μg, determined by LAL method.

文件资料

VSTM5 Protein, Human (His) 相关分类

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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The reconstitution calculator equation

Volume (to add to vial) = Mass (in vial) ÷ Desired Reconstitution Concentration

Volume (to add to vial) = Mass (in vial) ÷ Desired Reconstitution Concentration
= ÷

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2

The specific activity calculator equation

Specific Activity (Unit/mg) = 106 ÷ Biological Activity (ED50)

Specific Activity (Unit/mg) = 106 ÷ Biological Activity (ED50)
Unit/mg = 106 ÷ ng/mL

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产品名称:
VSTM5 Protein, Human (His)
目录号:
HY-P71443
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