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triazole derivatives

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19

抑制剂 & 激动剂

13

荧光染料

12

点击化学

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Cat. No. Product Name Target Research Area Chemical Structure
  • HY-156305

    Fluorescent Dye Others
    Coumarin-C2-exoBCN is a dye derivative of Coumarin (HY-N0709). Coumarin-C2-exoBCN contains the lyophilic bidentate macrocyclic ligand exo-BCN, which can further synthesize macrocyclic complexes. In click chemistry, exo-BCN can react with molecules containing azide groups to generate stable triazoles under catalyst-free conditions.
    Coumarin-C2-exo-BCN
  • HY-155327A

    Fluorescent Dye Others
    Cy3-PEG2-exo-BCN is a dye derivative of Cyanine 3 (Cy3) (HY-D0822) containing 2 PEG units. Cy3-PEG2-exo-BCN contains the lyophilic bidentate macrocyclic ligand BCN, which can further synthesize macrocyclic complexes. In click chemistry, exo-BCN can react with molecules containing azide groups to form stable triazoles in the absence of catalysts.
    Cy3-PEG2-exo-BCN
  • HY-D2120

    Fluorescent Dye Others
    Cy3-PEG3-endo-BCN is a dye derivative of Cyanine 3 (Cy3) (HY-D0822) containing 3 PEG units. Cy3-PEG3-endo-BCN contains the lyophilic bidentate macrocyclic ligand BCN, which can further synthesize macrocyclic complexes. In click chemistry, endo-BCN can react with molecules containing azide groups to form stable triazoles in the absence of catalysts.
    Cy3-PEG3-endo-BCN
  • HY-D2120A

    Fluorescent Dye Others
    Cy3-PEG3-exo-BCN is a dye derivative of Cyanine 3 (Cy3) (HY-D0822) containing 3 PEG units. Cy3-PEG3-exo-BCN contains the lyophilic bidentate macrocyclic ligand BCN, which can further synthesize macrocyclic complexes. In click chemistry, exo-BCN can react with molecules containing azide groups to form stable triazoles in the absence of catalysts.
    Cy3-PEG3-exo-BCN
  • HY-D2121

    Fluorescent Dye Others
    Cy3-PEG7-endo-BCN is a dye derivative of Cyanine 3 (Cy3) (HY-D0822) containing 7 PEG units. Cy3-PEG7-endo-BCN contains the lyophilic bidentate macrocyclic ligand BCN, which can further synthesize macrocyclic complexes. In click chemistry, endo-BCN can react with molecules containing azide groups to form stable triazoles in the absence of catalysts.
    Cy3-PEG7-endo-BCN
  • HY-D2121A

    Fluorescent Dye Others
    Cy3-PEG7-exo-BCN is a dye derivative of Cyanine 3 (Cy3) (HY-D0822) containing 7 PEG units. Cy3-PEG7-exo-BCN contains the lyophilic bidentate macrocyclic ligand BCN, which can further synthesize macrocyclic complexes. In click chemistry, exo-BCN can react with molecules containing azide groups to form stable triazoles in the absence of catalysts.
    Cy3-PEG7-exo-BCN
  • HY-D2149

    Fluorescent Dye Others
    Cy5-PEG7-exo-BCN is a dye derivative of Cyanine 5 (Cy5) (HY-D0821) containing 7 PEG units. Cy5-PEG7-exo-BCN contains the lyophilic bidentate macrocyclic ligand BCN, which can further synthesize macrocyclic complexes. In click chemistry, exo-BCN can react with molecules containing azide groups to form stable triazoles in the absence of catalysts.
    Cy5-PEG7-exo-BCN
  • HY-D2218

    Fluorescent Dye Others
    SiR-alkyne 是 N -荧光团硅罗丹明的丙炔甲酰胺衍生物。SiR-alkyne 在铜(I)存在下与叠氮化物衍生物反应形成1,2,3 -三唑键。
    SiR-alkyne
  • HY-157532

    Cholinesterase (ChE) Others
    AChE-IN-55,1,2,3-三唑肟衍生物,是 AChE (4.8 μM) 的抑制剂。
    AChE-IN-55
  • HY-144426

    Influenza Virus Infection
    Neuraminidase-IN-6 (Compound 5c) 是一种有效的 neuraminidase 抑制剂,IC50 为 0.11 μM。Neuraminidase-IN-6 是一种 1,3,4-三唑-3-乙酰胺衍生物。神经氨酸酶 (NA) 是开发抗流感活性分子的理想靶点。
    Neuraminidase-IN-6
  • HY-163107

    Bacterial Infection
    Antimycobacterial agent-7 (compound 4) 是 1,2,4-三唑类抗结核杆菌剂 (MIC: 2 μg/mL)。Antimycobacterial agent-7 抑制 Mtb KatG 并引起 Mtb 细胞内 ROS 的积累。而 ROS 产生氧化破坏,导致 Mtb 死亡。
    Antimycobacterial agent-7
  • HY-W282615

    Bacterial Infection
    Antibacterial agent 117,三唑衍生物,是一种抗菌剂。Antibacterial agent 117 对 R. prowazekii MetAP1 (RpMetAP1) 有抑制作用,其 IC50 值为 15 μM。Antibacterial agent 117 也可抑制立克次体生长,可用于感染的研究。
    Antibacterial agent 117
  • HY-D2204

    Phosphatase Fluorescent Dye Cancer
    SHP1-IN-1 (compound 5p) 是含有 Src 同源 2 结构域的蛋白酪氨酸磷酸酶 SHP1 的荧光探针。SHP1-IN-1 具有 SHP1 抑制活性、对 Fe3+ 离子的选择性和良好荧光特性。SHP1-IN-1 表现出聚集后猝灭 (ACQ) 效应,具有良好的抗干扰性和较低的检测限 (5.55 μM)。
    SHP1-IN-1
  • HY-149620

    Fluorescent Dye Others
    Cy5-PEG2-exo-BCN 是含有 2 个 PEG 单元的 Cyanine 5 (Cy5) (HY-D0821) 染料衍生物。Cy5-PEG2-exo-BCN 含有亲液性二齿大环配体 BCN,可进一步合成大环配合物。在点击化学中,BCN 在无催化剂的条件下,可与含叠氮基团的分子生成稳定的三氮唑。
    Cy5-PEG2-exo-BCN
  • HY-149618

    Fluorescent Dye Others
    Cy5-PEG3-endo-BCN 是含有 3 个 PEG 单元的 Cyanine 5 (Cy5) (HY-D0821) 染料衍生物。Cy5-PEG3-endo-BCN 含有亲液性二齿大环配体 endo-BCN,可进一步合成大环配合物。在点击化学中,endo-BCN 在无催化剂的条件下,可与含叠氮基团的分子生成稳定的三氮唑。
    Cy5-PEG3-endo-BCN
  • HY-149619

    Fluorescent Dye Others
    Cy5-PEG7-endo-BCN 是含有 7 个 PEG 单元的 Cyanine 5 (Cy5) (HY-D0821) 染料衍生物。Cy5-PEG7-endo-BCN 含有亲液性二齿大环配体 endo-BCN,可进一步合成大环配合物。在点击化学中,endo-BCN 在无催化剂的条件下,可与含叠氮基团的分子生成稳定的三氮唑。
    Cy5-PEG7-endo-BCN
  • HY-155327

    Fluorescent Dye Others
    Cy3-PEG2-endo-BCN 是含有 2 个 PEG 单元的 Cyanine 3 (Cy3) (HY-D0822) 染料衍生物。Cy3-PEG2-endo-BCN 含有亲液性二齿大环配体 endo-BCN,可进一步合成大环配合物。在点击化学中,endo-BCN 在无催化剂的条件下,可与含叠氮基团的分子生成稳定的三氮唑。
    Cy3-PEG2-endo-BCN
  • HY-162479

    Phosphatase Amyloid-β Metabolic Disease
    PTP1B-IN-26 (化合物 7a) 是一种苯基硫代半卡巴脲-苯氧基-1,2,3-三唑-N-苯乙酰胺衍生物。PTP1B-IN-26 是蛋白酪氨酸磷酸酶 1B(PTP-1B)的竞争性抑制剂。PTP1B-IN-26 可用于 2 型糖尿病的研究。
    PTP1B-IN-26
  • HY-19599

    (+)-Vorozole; R83842

    Cytochrome P450 Cancer
    Vorozole 是一种有效的,选择性的,具有口服活性的非甾体 芳香酶 抑制剂。Vorozole 表现出体内抗肿瘤作用。Vorozole 具有研究乳腺癌的潜力。
    Vorozole

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