1. Signaling Pathways
  2. Immunology/Inflammation
  3. Salt-inducible Kinase (SIK)

Salt-inducible Kinase (SIK) (盐诱导激酶)

Salt-inducible Kinases (SIK) are a family of related serine-threonine kinases. In cultured adrenocortical cells, SIK1 is rapidly but transiently induced by adrenocorticotropin (ACTH) treatment, suggesting that it contributes to ACTH-mediated induction of steroidogenic enzymes. SIK2 is found in adipocytes and phosphorylates a specific serine residue. Members of the SIK family are emerging as important modulators of key processes such as steroid hormone biosynthesis by the adrenal cortex in adipocytes.

Salt-inducible Kinase (SIK) 相关产品 (1):

目录号 产品名 作用方式 纯度
  • HY-N1570
    Pterosin B Inhibitor 99.08%
    Pterosin B 是一种从蕨菜 (Pteridium aquilinum) 中发现的茚满酮,是盐诱导性激酶 3 (Sik3) 信号转导的抑制剂。Pterosin B 通过抑制 Sik3 预防小鼠软骨细胞肥大和骨关节炎。
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