2. Metabolic Enzyme/Protease Neuronal Signaling GPCR/G Protein
  3. Endogenous Metabolite Adrenergic Receptor
  4. L-Epinephrine sulfate

L-Epinephrine sulfate  (Synonyms: (-)-Epinephrine sulfate; L-Adrenaline sulfate; (-)-Adrenalin sulfate)

目录号: HY-122304
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L-Epinephrine ((-)-Epinephrine, L-Adrenaline) sulfate 是一种由肾上腺髓质分泌的口服活性激素。L-Epinephrine sulfate 是一种 α-adrenergic 和 β-adrenergic 受体激动剂。L-Epinephrine sulfate 可用于研究过敏反应。L-Epinephrine sulfate 具有心脏骤停研究潜力[4]。

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L-Epinephrine sulfate Chemical Structure

L-Epinephrine sulfate Chemical Structure

CAS No. : 52455-32-0

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L-Epinephrine sulfate 相关抗体

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α adrenergic receptor β adrenergic receptor

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生物活性

L-Epinephrine ((-)-Epinephrine, L-Adrenaline) sulfate is a orally active hormone secreted by the medulla of the adrenal glands. L-Epinephrine sulfate is an α-adrenergic and β-adrenergic receptor agonist. L-Epinephrine sulfate can be used in the research of anaphylaxis. L-Epinephrine sulfate has the potential for the research of cardiac arrest[1][2][3][4].

IC50 & Target

β adrenergic receptor

 

体内研究
(In Vivo)

L-Epinephrine sulfate (0.75, 1.5, 3 mg/kg; i.p.) exerts oxidative and nitrative stress in rats, increased damage to lipids and proteins, and damage of cardiomyocytes and cytogenetic damage in rats[2].
L-Epinephrine sulfate (0.02, 0.03 mg/kg) increases ABP’s and to some extent also CePP, but significantly decreases organ and brain perfusion in adult pigs[3].
L-Epinephrine sulfate (0.1 mg/kg; s.c.) enhances memory in young adult rats, in part, by increasing blood glucose levels needed to modulate memory[6].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

Animal Model: 220-280 g, 18 weeks Wistar rats[2]
Dosage: 0.75, 1.5, 3 mg/kg
Administration: IP
Result: Induced a significant rise in CAT activity, MDA level, PCC, NO2−, and 3-NT and a significant decrease in SOD activity, and exerted an increase in total activity of LDH, LDH1, and LDH2 isoenzymes.
Animal Model: 24-25 month male Fischer-344 rats[6]
Dosage: 0.1 mg/kg
Administration: S.c.
Result: Enhanced memory in young adult rats, in part, by increasing blood glucose levels needed to modulate memory.
Formula

C9H13NO3.xH2O4S
CAS 号
结构分类
初始来源
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
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参考文献

L-Epinephrine sulfate 相关分类

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Keywords:

L-Epinephrine52455-32-0(-)-EpinephrineL-Adrenaline(-)-AdrenalinEndogenous MetaboliteAdrenergic ReceptorBeta Receptororally activeanaphylaxiscardiac arrestInhibitorinhibitorinhibit

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