Integrin alpha 6 抗体 (YA5132)

Integrin alpha 6 Antibody (YA5132) is a Mouse-derived and non-conjugated monoclonal antibody, targeting to Integrin alpha 6.

Integrin α6 是一种整合素蛋白，可与不同 β 亚基形成异源二聚体。Integrin α6/β1 (ITGA6:ITGB1) 是血小板表面的 laminin 受体 (by similar)，同时存在于卵母细胞中并参与精卵融合过程 (by similar)。Integrin α6/β4 (ITGA6:ITGB4) 是上皮细胞中 laminin 的受体，在半桥粒结构中发挥关键作用 (by similar)。ITGA6:ITGB4 能与 NRG1 (通过 EGF 结构域) 结合，这对 NRG1-ERBB 信号传导至关重要。此外，ITGA6:ITGB4 还能与 IGF1 和 IGF2 结合，分别对 IGF1 和 IGF2 信号传导起关键作用。

P23229

Predicted band size: 127 kDa;

affinity purified.

Non-conjugated

Unmodified

Primary Antibody; Mouse Monoclonal Antibody

Monoclonal

Mouse

Human, Mouse, Rat, Bovine, Dog, Pig

WB: 1:1000-1:2000; ICC/IF: 1:100-1:500

WB, ICC/IF

液体

Supplied in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.

Shipping with blue ice.

Purified recombinant human Integrin α6 (N-terminus) protein fragments expressed in E.coli.