2. 抗体
  3. 一抗
  4. 单克隆抗体 重组抗体
  5. STAT6 抗体 (YA051)

STAT6 抗体 (YA051)

目录号: HY-P80347
COA 抗体使用指南 技术支持

STAT6 Antibody (YA051) 是一个兔来源、无偶联标记、抗 STAT6 的 IgG 单克隆抗体。

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规格 价格 是否有货 数量
10 μL ￥470 In-stock
50 μL ￥1220 In-stock
100 μL ￥2000 In-stock
250 μL   询价  

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Top Publications Citing Use of Products

【WB: 蛋白质免疫印迹; IHC-P: 石蜡切片样本的免疫组织化学; IHC-F: 冰冻切片样本的免疫组织化学; ICC/IF: 细胞免疫荧光; IF-Tissue: 组织免疫荧光; mIHC: 多重荧光免疫组化; IP: 免疫沉淀; ChIP: 染色质免疫沉淀; FC: 流式细胞术; ELISA: 酶联免疫吸附试验】

  • 生物活性

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描述

STAT6 Antibody (YA051) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to STAT6.
研究背景

STAT6（信号转导和转录激活剂6）是一种多功能蛋白，在信号转导和转录激活中发挥双重作用。它特别参与介导白细胞介素 4 (IL-4) 和白细胞介素 3 (IL-3) 触发的信号传导通路。STAT6可以与相关家族成员形成同二聚体或异二聚体，促进其参与各种细胞过程。此外，STAT6 通过其 C 端 LXXLL 基序与核受体共激活剂 NCOA1 相互作用，表明其在调节基因表达方面具有潜在作用。这种相互作用进一步强调了 STAT6 参与转录调控，突出了它在协调细胞通路中的信号事件和转录反应方面的多功能性。
标签

Free
基因 ID
蛋白数据库
中文名
STAT6 抗体
同用名
12S1644 antibody; D12S1644 antibody; IL 4 STAT antibody; IL-4 Stat antibody; IL4 STAT antibody; Interleukin 4 Induced antibody; Interleukin 4 Induced Transcription Factor IL4 STAT antibody; Signal transducer and activator of transcription 6 antibody; Signal Transducer And Activator Of Transcription 6 Interleukin 4 Induced antibody; Signal Transducer And Activator Of Transcription 6 Nirs Variant 1 antibody; Signal transducer and activator of transcription 6, interleukin 4 induced antibody; STAT 6 antibody; STAT interleukin4 induced antibody; STAT, interleukin4 induced antibody; Stat6 antibody; STAT6_HUMAN antibody; STAT6B antibody; STAT6C antibody; Transcription factor IL 4 STAT antibody;
分子量

Predicted band size: 94 kDa;Observed band size: 100-110 kDa
纯度

Protein A affinity purified.
亚细胞定位

Cytoplasm, Nucleus.
偶联

Non-conjugated
修饰

Unmodified
RRID
研究领域

Signal Transduction
产品类别

Primary Antibody; Recombinant Rabbit Monoclonal Antibody
克隆性

Recombinant, Monoclonal
宿主

Rabbit
反应物种

Human, Mouse
推荐稀释比例

WB: 1:500; ICC/IF: 1:50; IHC-P: 1:50-1:200

  • Western blot analysis of extracts from 3T3 (lane 1) using STAT6 antibody. Proteins were transferred to a PVDF membrane and blocked with 5% nonfat powdered milk in PBST for 2 hour at room temperature. The primary antibody (1/2000) and Loading control antibody (GAPDH, 1/3000) was diluted with 5% nonfat powdered milk in PBST at 4°C overnight. Goat Anti-Rabbit IgG-HRP Secondary Antibody (1/8,000) was incubated for 45min at room temperature.
应用

WB, ICC/IF, IHC-P, IP
性状

液体
组分

Supplied in 1*TBS (pH7.4), 0.05% BSA and 40% Glycerol. Preservative: 0.05% Sodium Azide.
保存条件 & 期限

Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.
运输条件

Shipping with blue ice.
同型

IgG
敏感性

Endogenous
免疫原

Synthetic peptide within human STAT6 C terminal.
数据库

Entrez Gene: 6778 Human ; 20852 Mouse ;

SwissProt: P42226 Human ; P52633 Mouse ;

OMIM: 620532 Human

文件资料

COA (193 KB)

抗体使用指南 (1083 KB)

STAT6 Antibody (YA051) 相关分类

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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目录号：
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