PLA2G4B - phospholipase A2 group IVB Gene

中文名称：磷脂酶 A2 组 IVB

种属: Homo sapiens

同用名: HsT16992; cPLA2-beta

关于 PLA2G4B

功能概要

该基因编码胞质磷脂酶 A2 蛋白家族的一个成员。磷脂酶 A2 水解磷脂的 sn-2 键，释放溶血磷脂和脂肪酸。这种酶可能与线粒体和早期内体有关。大多数组织还表达从上游基因到该基因的通读转录本，其中一些可能编码融合蛋白，将上游基因的 N 端 (包括其 JmjC 结构域) 与该基因的几乎完整编码区 (包括 C2 和胞质磷脂酶 A2 结构域。[RefSeq 提供，2008 年 7 月]

This gene encodes a member of the cytosolic Phospholipase A2 protein family. Phospholipase A2 enzymes hydrolyze the sn-2 bond of Phospholipids, releasing lysophospholipids and fatty acids. This Enzyme may be associated with mitochondria and early endosomes. Most tissues also express read-through transcripts from the upstream gene into this gene, some of which may encode fusion proteins combining the N-terminus of the upstream gene including its JmjC domain with the almost complete coding region of this gene, including the C2 and cytoplasmic Phospholipase A2 domains. [provided by RefSeq, Jul 2008]