2. Gene
  3. FLOT1 - flotillin 1 Gene

FLOT1 - flotillin 1 Gene

  • 基因
  • 蛋白
  • 疾病
  • 相关产品
  • 直系同源

中文名称：flotillin 1

种属: Homo sapiens

基因 ID: 10211 | 基因类型: protein coding

关于 FLOT1

Cytogenetic location: 6p21.33 Genomic coordinates (GRCh38): 6:30,727,709-30,742,687 (from NCBI)

This gene has 12 transcripts (splice variants), 1 gene allele, 279 orthologues and 1 paralogue. Ubiquitous expression in adrenal (RPKM 66.3), heart (RPKM 56.6) and 25 other tissues.

功能概要

该基因编码一种定位于小窝的蛋白质，小窝是内细胞膜上的小区域。这种蛋白质在囊泡运输和细胞形态学中发挥作用。可变剪接导致多个转录本变体。[RefSeq 提供，2016 年 1 月]

This gene encodes an protein that localizes to the caveolae, which are small domains on the inner cell membranes. This protein plays a role in vesicle trafficking and cell morphology. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jan 2016]

FLOT1 基因产物(2)

mRNA Protein Name
NM_001318875.2 NP_001305804.1 flotillin-1 isoform 2
NM_005803.4 NP_005794.1 flotillin-1 isoform 1

FLOT1 蛋白结构

Band_7

Band_7: SPFH domain / Band 7 family (4 - 184)

  • 0
  • 100
  • 200
  • 300
  • 400
  • 427 a.a.
蛋白主名 其他名称

flotillin-1

integral membrane component of caveolae

关联疾病

疾病名称 别名
Mycobacterium Marinum

Mycobacterium Marinum Infection

Fish Tank Granuloma

M. Marinum
Open-Angle Glaucoma

Glaucoma Simplex

Pigmentary Glaucoma

Wide-Angle Glaucoma

Glaucoma, Open-Angle

Open Angle Glaucoma

Glaucoma Open-Angle

Chronic Simple Glaucoma

Coag - [Chronic Open-Angle Glaucoma]

Csg - [Chronic Simple Glaucoma]

Poag - [Primary Open-Angle Glaucoma]

Oag - [Open-Angle Glaucoma]

Chronic Glaucoma

Chronic Open Angle Glaucoma

Simple Glaucoma

Chronic Noncongestive Glaucoma

Ltg - [Low Tension Glaucoma]

Noncongestive Glaucoma

Nonobstructive Glaucoma

Normal Pressure Glaucoma

Primary Low Tension Glaucoma

Low-Tension Glaucoma

Residual Stage Low Tension Glaucoma

Open Cleft Glaucoma
Cortical Dysplasia, Complex, With Other Brain Malformations 6

Complex Cortical Dysplasia With Other Brain Malformations 6

CDCBM6

Cdcbm56

Dysplasia ,Cortical, Complex, With Other Brain Malformations, Type 6
Alzheimer Disease, Familial, 1

Alzheimer Disease

Alzheimer'S Disease

Presenile And Senile Dementia

AD1

Alzheimer Disease, Susceptibility To

Alzheimer Disease, Late-Onset, Susceptibility To

Alzheimer Disease 1, Familial

AD

Familial Alzheimer Disease

Alzheimer Disease, Late-Onset

Alzheimers Dementia

Alzheimer Dementia

Alzheimer Sclerosis

Alzheimer Syndrome

Alzheimer-Type Dementia

Dat

Primary Senile Degenerative Dementia

Sdat

Alzheimer Disease 1

Autosomal Dominant Alzheimer Disease

Early-Onset Alzheimer Disease With Cerebral Amyloid Angiopathy

Late Onset Alzheimer Disease

Alzheimers Disease

Alzheimer Disease, Early-Onset, With Cerebral Amyloid Angiopathy

Late-Onset Alzheimers Disease

Alzheimer'S Disease Pathway Kegg

Dementia Due To Alzheimer'S Disease

Alzheimer Disease Type 1

Alzheimers
Bardet-Biedl Syndrome

Bbs

Biedl-Bardet Syndrome
疾病名称 别名
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

相关产品

Pre-clinical Phase
生物活性分子 (1)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-RS04982 FLOT1 Human Pre-designed siRNA Set A Pre-designed Sets / 否

直系同源

种属 基因名 来源 基因 ID
Rattus norvegicus FLOT1 RGD RGD:70991
Felis catus FLOT1 VGNC VGNC:62294
Macaca mulatta FLOT1 VGNC VGNC:72674
Bos taurus FLOT1 VGNC VGNC:29036
Canis familiaris FLOT1 VGNC VGNC:40903
Mus musculus FLOT1 MGD MGI:1100500
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