2. Gene
  3. EMP3 - epithelial membrane protein 3 Gene

EMP3 - epithelial membrane protein 3 Gene

  • 基因
  • 蛋白
  • 疾病
  • 相关产品
  • 直系同源

中文名称：上皮膜蛋白 3

种属: Homo sapiens

同用名: YMP

基因 ID: 2014 | 基因类型: protein coding

关于 EMP3

Cytogenetic location: 19q13.33 Genomic coordinates (GRCh38): 19:48,325,552-48,330,553 (from NCBI)

This gene has 9 transcripts (splice variants), 239 orthologues and 10 paralogues. Ubiquitous expression in bone marrow (RPKM 63.7), appendix (RPKM 40.0) and 24 other tissues.

功能概要

该基因编码的蛋白质属于 PMP-22/EMP/MP20 蛋白质家族。该蛋白质包含四个跨膜结构域和两个 N-连接的糖基化位点。它被认为参与细胞增殖、细胞间相互作用并作为肿瘤抑制因子发挥作用。可变剪接导致多个转录本变体。[RefSeq 提供，2015 年 9 月]

The protein encoded by this gene belongs to the PMP-22/EMP/MP20 family of proteins. The protein contains four transmembrane domains and two N-linked glycosylation sites. It is thought to be involved in cell proliferation, cell-cell interactions and function as a tumor suppressor. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Sep 2015]

EMP3 基因产物(2)

mRNA Protein Name
NM_001313905.1 NP_001300834.1 epithelial membrane protein 3
NM_001425.3 NP_001416.1 epithelial membrane protein 3

EMP3 蛋白结构

PMP22_Claudin

PMP22_Claudin: PMP-22/EMP/MP20/Claudin family (1 - 156)

  • 0
  • 100
  • 163 a.a.
蛋白主名 其他名称

epithelial membrane protein 3

EMP-3

关联疾病

疾病名称 别名
Adult Oligodendroglioma

Adult Brain Oligodendroglioma

Grade Ii Adult Oligodendroglial Tumor

Oligodendroglioma, Adult
Charcot-Marie-Tooth Disease

Cmt

Hmsn

Hereditary Motor And Sensory Neuropathy

Pma

Cmt - Charcot-Marie-Tooth Disease

Charcot Marie Tooth Disease

Charcot-Marie-Tooth Hereditary Neuropathy

Charcot-Marie-Tooth Syndrome

Peroneal Muscular Atrophy

Hereditary Motor And Sensory Neuropathies
疾病名称 别名
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

相关产品

Pre-clinical Phase
生物活性分子 (1)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-RS04361 EMP3 Human Pre-designed siRNA Set A Pre-designed Sets / 否

直系同源

种属 基因名 来源 基因 ID
Canis familiaris EMP3 VGNC VGNC:40354
Bos taurus EMP3 VGNC VGNC:28483
Macaca mulatta EMP3 VGNC VGNC:72215
Mus musculus EMP3 MGD MGI:1098729
Rattus norvegicus EMP3 RGD RGD:621094
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