2. Gene
  3. Celsr3 - cadherin, EGF LAG seven-pass G-type receptor 3 Gene

Celsr3 - cadherin, EGF LAG seven-pass G-type receptor 3 Gene

  • 基因
  • 蛋白
  • 相关产品
  • 直系同源

种属: Mus musculus

同用名: Fmi1; Adgrc3; flamingo; mKIAA0812

基因 ID: 107934 | 基因类型: protein coding

关于 Celsr3

功能概要

Predicted to enable G protein-coupled receptor activity and calcium ion binding activity. Involved in dopaminergic neuron axon guidance; planar cell polarity pathway involved in axon guidance; and serotonergic neuron axon guidance. Acts upstream of or within several processes, including cilium assembly; generation of neurons; and regulation of protein phosphorylation. Predicted to be located in plasma membrane. Predicted to be integral component of membrane. Is expressed in several structures, including central nervous system; embryo ectoderm; epiblast; peripheral nervous system; and retina. Orthologous to human CELSR3 (Cadherin EGF LAG seven-pass G-type receptor 3). [provided by Alliance of Genome Resources, Apr 2022]

Celsr3 基因产物(3)

mRNA Protein Name
NM_001359572.1 NP_001346501.1 cadherin EGF LAG seven-pass G-type receptor 3 isoform 1 precursor
NM_001359573.1 NP_001346502.1 cadherin EGF LAG seven-pass G-type receptor 3 isoform 2 precursor
NM_080437.3 NP_536685.2 cadherin EGF LAG seven-pass G-type receptor 3 isoform 3 precursor
基因本体论
  • 生物过程
  • 细胞组分
生物过程 GO 注释 逻辑证据 参考文献 来源
involved in Wnt signaling pathway, planar cell polarity pathway IMP
IMP: 通过突变表型推断
21106844 MGI
acts upstream of or within axonal fasciculation IMP
IMP: 通过突变表型推断
15778712 MGI
acts upstream of or within cilium assembly IGI
IGI: 通过遗传相互作用推断
20473291 MGI
involved in dopaminergic neuron axon guidance IMP
IMP: 通过突变表型推断
21106844 MGI
acts upstream of or within motor neuron migration IMP
IMP: 通过突变表型推断
20631168 MGI
acts upstream of or within regulation of protein localization IGI
IGI: 通过遗传相互作用推断
20473291 MGI
acts upstream of or within regulation of protein phosphorylation IMP
IMP: 通过突变表型推断
24305805 MGI
involved in serotonergic neuron axon guidance IMP
IMP: 通过突变表型推断
21106844 MGI
细胞组分 GO 注释 逻辑证据 参考文献 来源
is active in glutamatergic synapse IDA
IDA: 通过直接分析推断
34407949 MGI
is active in postsynaptic density membrane IDA
IDA: 通过直接分析推断
34407949 MGI
is active in presynaptic active zone membrane IDA
IDA: 通过直接分析推断
34407949 MGI
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断
蛋白主名 其他名称

cadherin EGF LAG seven-pass G-type receptor 3

cadherin, EGF LAG seven-pass G-type receptor 3 (flamingo homolog, Drosophila)

相关产品

Pre-clinical Phase
生物活性分子 (4)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-175232 GL64 / 否
HY-RS02467 CELSR3 Human Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS18305 Celsr3 Mouse Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS24783 Celsr3 Rat Pre-designed siRNA Set A Pre-designed Set / 否

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Celsr3 NCBI NCBI:1951
嗨！很高兴为您提供帮助！

尊敬的 MCE 客户您好，
请您选择所在区域，我们将转接对应客服为您服务！

热门区域

A

B

C

F

G

H

J

L

N

Q

S

T

X

Y

Z

热 A B C F G H J L N Q S T X Y Z