2. Gene
  3. Ppp1r15b - protein phosphatase 1, regulatory subunit 15B Gene

Ppp1r15b - protein phosphatase 1, regulatory subunit 15B Gene

  • 基因
  • 蛋白
  • 相关产品
  • 直系同源

种属: Mus musculus

同用名: CReP; 1810033K10Rik; C530022L24Rik

基因 ID: 108954 | 基因类型: protein coding

关于 Ppp1r15b

功能概要

Enables protein Phosphatase regulator activity. Involved in negative regulation of endoplasmic reticulum stress-induced eIF2 alpha phosphorylation and peptidyl-serine dephosphorylation. Acts upstream of or within ER overload response and response to hydrogen peroxide. Part of protein Phosphatase type 1 complex. Is expressed in compacted morula and inner cell mass. Orthologous to human PPP1R15B (protein Phosphatase 1 regulatory subunit 15B). [provided by Alliance of Genome Resources, Apr 2022]

Ppp1r15b 基因产物(1)

mRNA Protein Name
NM_133819.3 NP_598580.1 protein phosphatase 1 regulatory subunit 15B
基因本体论
  • 分子功能
  • 生物过程
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables protein phosphatase regulator activity IDA
IDA: 通过直接分析推断
14638860 MGI
生物过程 GO 注释 逻辑证据 参考文献 来源
acts upstream of or within ER overload response IDA
IDA: 通过直接分析推断
14638860 MGI
acts upstream of or within ER overload response IMP
IMP: 通过突变表型推断
14638860 MGI
acts upstream of or within response to endoplasmic reticulum stress IMP
IMP: 通过突变表型推断
14638860 MGI
acts upstream of or within response to hydrogen peroxide IMP
IMP: 通过突变表型推断
14638860 MGI
acts upstream of or within response to oxidative stress IDA
IDA: 通过直接分析推断
14638860 MGI
acts upstream of or within response to oxidative stress IMP
IMP: 通过突变表型推断
14638860 MGI
细胞组分 GO 注释 逻辑证据 参考文献 来源
part of protein phosphatase type 1 complex IDA
IDA: 通过直接分析推断
14638860 MGI
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断
蛋白主名 其他名称

protein phosphatase 1 regulatory subunit 15B

constitutive repressor of eIF2alpha phosphorylation

protein phosphatase 1, regulatory (inhibitor) subunit 15b

相关产品

Pre-clinical Phase
生物活性分子 (9)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-123960 Raphin1 Inhibitor 99.75% 否
HY-123960A Raphin1 acetate Inhibitor 99.93% 否
HY-18956 (E/Z)-Icerguastat Inhibitor 99.44% 否
HY-123960B (E/Z)-Raphin1 Inhibitor / 否
HY-18956B (E/Z)-Icerguastat acetate Inhibitor / 否
HY-RS10987 PPP1R15B Human Pre-designed siRNA Set A Pre-designed Set / 否
HY-18956A (E/Z)-Icerguastat hydrochloride Inhibitor / 否
HY-RS19102 Ppp1r15b Mouse Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS25591 Ppp1r15b Rat Pre-designed siRNA Set A Pre-designed Set / 否

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Ppp1r15b NCBI NCBI:84919
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