2. Gene
  3. Acat2 - acetyl-Coenzyme A acetyltransferase 2 Gene

Acat2 - acetyl-Coenzyme A acetyltransferase 2 Gene

  • 基因
  • 蛋白
  • 相关产品
  • 直系同源

中文名称：乙酰辅酶 A 乙酰转移酶 2

种属: Mus musculus

同用名: Tcp-1x; Tcp1-rs1

基因 ID: 110460 | 基因类型: protein coding

关于 Acat2

Chromosome 17: 13,161,777-13,179,634 reverse strand.GRCm39:CM001010.3

This gene has 4 transcripts (splice variants), 212 orthologues, 6 paralogues and is associated with 12 phenotypes. Ubiquitous expression in CNS E11.5 (RPKM 65.2), liver adult (RPKM 62.8) and 28 other tissues.

功能概要

预计该基因编码的蛋白可启动乙酰辅酶 A C-乙酰转移酶活性。参与肠道胆固醇吸收的正向调节。位于线粒体中。以多种结构表达，包括消化系统；泌尿生殖系统；外皮系统；神经系统;和感觉器官。该基因的人类直系同源物与冠状动脉疾病有关。与人类 ACAT2（乙酰辅酶 A 乙酰转移酶 2）同源。 [由基因组资源联盟提供，2022 年 4 月]

Predicted to enable acetyl-CoA C-acetyltransferase activity. Involved in positive regulation of intestinal Cholesterol absorption. Located in mitochondrion. Is expressed in several structures, including alimentary system; genitourinary system; integumental system; nervous system; and sensory organ. Human ortholog(s) of this gene implicated in coronary artery disease. Orthologous to human ACAT2 (acetyl-CoA acetyltransferase 2). [provided by Alliance of Genome Resources, Apr 2022]

Acat2 基因产物(1)

mRNA Protein Name
NM_009338.3 NP_033364.2 acetyl-CoA acetyltransferase, cytosolic

Acat2 蛋白结构

PRK05790

PRK05790: PRK05790 (7 - 395)

  • 0
  • 100
  • 200
  • 300
  • 397 a.a.
蛋白主名 其他名称

acetyl-CoA acetyltransferase, cytosolic

cytosolic acetoacetyl-CoA thiolase

t-complex protein 1, related sequence 1

相关产品

Clinical Phase
生物活性分子 (6)
目录号 产品名 作用方式
纯度 Phase
HY-13215 Avasimibe Inhibitor 99.85% Phase 3
HY-100401 Pactimibe Inhibitor 99.98% Phase 3
HY-100401A Pactimibe sulfate Inhibitor ≥98.0% Phase 3
HY-100400A K-604 dihydrochloride Inhibitor 99.42% Phase 2
HY-100399A Nevanimibe hydrochloride Inhibitor 99.49% Phase 2
HY-100399 Nevanimibe Inhibitor / Phase 2

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Acat2 NCBI NCBI:39
Rattus norvegicus Acat2 NCBI NCBI:308100
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