2. Gene
  3. Vegfc - vascular endothelial growth factor C Gene

Vegfc - vascular endothelial growth factor C Gene

  • 基因
  • 蛋白
  • 相关产品
  • 直系同源

种属: Rattus norvegicus

基因 ID: 114111 | 基因类型: protein coding

关于 Vegfc

功能概要

Enables vascular endothelial growth factor receptor 3 binding activity. Involved in several processes, including positive regulation of blood vessel endothelial cell migration; positive regulation of protein autophosphorylation; and regulation of vascular endothelial growth factor receptor signaling pathway. Acts upstream of or within positive regulation of neuroblast proliferation. Predicted to be located in membrane. Predicted to be active in extracellular space. Biomarker of colon adenocarcinoma. Human ortholog(s) of this gene implicated in breast carcinoma and hereditary lymphedema ID. Orthologous to human VEGFC (vascular endothelial growth factor C). [provided by Alliance of Genome Resources, Apr 2022]

Vegfc 基因产物(1)

mRNA Protein Name
NM_053653.2 NP_446105.1 vascular endothelial growth factor C precursor
基因本体论
  • 分子功能
  • 生物过程
分子功能 GO 注释 逻辑证据 参考文献 来源
enables vascular endothelial growth factor receptor 3 binding IMP
IMP: 通过突变表型推断
11683876 RGD
生物过程 GO 注释 逻辑证据 参考文献 来源
involved in angiogenesis IMP
IMP: 通过突变表型推断
12706123 RGD
involved in negative regulation of blood pressure IMP
IMP: 通过突变表型推断
19412173 RGD
involved in positive regulation of blood vessel endothelial cell migration IMP
IMP: 通过突变表型推断
12706123 RGD
acts upstream of or within positive regulation of cell population proliferation IDA
IDA: 通过直接分析推断
16462734 RGD
involved in positive regulation of epithelial cell proliferation IMP
IMP: 通过突变表型推断
16618418 RGD
acts upstream of or within positive regulation of neuroblast proliferation IDA
IDA: 通过直接分析推断
16462734 RGD
involved in positive regulation of protein autophosphorylation IMP
IMP: 通过突变表型推断
11683876 RGD
involved in positive regulation of protein secretion IMP
IMP: 通过突变表型推断
16618418 RGD
involved in regulation of vascular endothelial growth factor receptor signaling pathway IMP
IMP: 通过突变表型推断
11683876 RGD
involved in response to xenobiotic stimulus IEP
IEP: 通过表达模式推断
19147132 RGD
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断
蛋白主名 其他名称

vascular endothelial growth factor C

VEGF-C

VRP

flt4 ligand

flt4-L

vascular endothelial growth factor-related protein

相关产品

Clinical Phase
生物活性分子 (2)
目录号 产品名 作用方式
纯度 Phase
HY-P3369 Gersizangitide 98.05% Phase 2
HY-152293 EVT801 Inhibitor / Phase 1
抗体抑制剂 (1)
目录号 产品名 作用方式
纯度 Phase
HY-P990675 VGX-100 Inhibitor 99.54% Phase 1
Pre-clinical Phase
生物活性分子 (9)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-116624 MAZ51 99.96% 否
HY-N2187 Deoxyshikonin 99.96% 否
HY-132305 VEGFR-3-IN-1 Inhibitor 98.76% 否
HY-176347S Alpha Feto Protein, Arg-13C6,15N4, Lys-13C6,15N2 / 否
HY-RS15637 VEGFC Human Pre-designed siRNA Set A Pre-designed Set / 否
HY-174507 Human VEGFD mRNA / 否
HY-174508 Human VEGFC mRNA / 否
HY-RS16674 Vegfc Mouse Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS23109 Vegfc Rat Pre-designed siRNA Set A Pre-designed Set / 否
抗体抑制剂 (1)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-P9920A Ramucirumab (anti-VEGFR) Antagonist 99.9% 否

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Vegfc NCBI NCBI:7424
Mus musculus Vegfc NCBI NCBI:22341
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