1. Anti-infection
    Metabolic Enzyme/Protease
  2. Bacterial
    HIF/HIF Prolyl-Hydroxylase
  3. Deoxyshikonin

Deoxyshikonin 

目录号: HY-N2187
产品使用指南

Deoxyshikonin 从紫草 Lithospermum erythrorhizon 中分离,具有抗肿瘤活性。Deoxyshikonin增加 HMVEC-dLy 中 VEGF-CVEGF-A mRNA 的表达,促进 HIF-1α 和 HIF-1β 亚基相互作用,并与 HIF 特异性 DNA 序列结合。Deoxyshikonin 在体外具有促血管生成作用。Deoxyshikonin 显示出显着的协同抗微生物活性, S. pneumonia (MIC =17μg/mL),也显示出对 MRSA 的显着抑制活性。

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Deoxyshikonin Chemical Structure

Deoxyshikonin Chemical Structure

CAS No. : 43043-74-9

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Top Publications Citing Use of Products
  • 生物活性

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  • 参考文献

Description

Deoxyshikonin is isolated from Lithospermum erythrorhizon Sieb with antitumor activity. Deoxyshikonin increases the expression of VEGF-C and VEGF-A mRNA in HMVEC-dLy, promotes HIF-1α and HIF-1β subunit interaction and binds to specific DNA sequences targeted by HIF, indicates a prolymphangiogenesis as well as a proangiogenesis effect in vitro[1]. Deoxyshikonin shows significant synergic antimicrobial activity with tetracycline against S. pneumonia (MIC=17 μg/mL), also shows significantly inhibitory activities against MRSA[2].

Molecular Weight

272.30

Formula

C₁₆H₁₆O₄

CAS No.

43043-74-9

SMILES

O=C1C(CC/C=C(C)/C)=CC(C2=C1C(O)=CC=C2O)=O

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Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

References
  • 摩尔计算器

  • 稀释计算器

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass   Concentration   Volume   Molecular Weight *
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The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
× = ×
C1   V1   C2   V2

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产品名称:
Deoxyshikonin
目录号:
HY-N2187
需求量:

Deoxyshikonin

Cat. No.: HY-N2187