2. Gene
  3. Alas1 - aminolevulinic acid synthase 1 Gene

Alas1 - aminolevulinic acid synthase 1 Gene

  • 基因
  • 蛋白
  • 相关产品
  • 直系同源

种属: Mus musculus

同用名: ALAS; ALAS-N; Alas-1; Alas-h

基因 ID: 11655 | 基因类型: protein coding

关于 Alas1

功能概要

Predicted to enable 5-aminolevulinate synthase activity and identical protein binding activity. Predicted to be involved in erythrocyte development; heme biosynthetic process; and Hemoglobin biosynthetic process. Located in mitochondrion. Is expressed in several structures, including adrenal gland; alimentary system; liver; and male reproductive system. Orthologous to human ALAS1 (5'-aminolevulinate synthase 1). [provided by Alliance of Genome Resources, Apr 2022]

Alas1 基因产物(2)

mRNA Protein Name
NM_001291835.1 NP_001278764.1 5-aminolevulinate synthase, non-specific, mitochondrial precursor
NM_020559.2 NP_065584.2 5-aminolevulinate synthase, non-specific, mitochondrial precursor
基因本体论
  • 分子功能
  • 生物过程
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables 5-aminolevulinate synthase activity IMP
IMP: 通过突变表型推断
24821812 MGI
生物过程 GO 注释 逻辑证据 参考文献 来源
involved in heme A biosynthetic process IMP
IMP: 通过突变表型推断
33307066 MGI
involved in heme B biosynthetic process IMP
IMP: 通过突变表型推断
33307066 MGI
involved in heme O biosynthetic process IMP
IMP: 通过突变表型推断
33307066 MGI
细胞组分 GO 注释 逻辑证据 参考文献 来源
is active in mitochondrial matrix IDA
IDA: 通过直接分析推断
34900592 MGI
is active in mitochondrial matrix IMP
IMP: 通过突变表型推断
33307066 MGI
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断
蛋白主名 其他名称

5-aminolevulinate synthase, non-specific, mitochondrial

5-aminolevulinate synthase, nonspecific, mitochondrial

5-aminolevulinic acid synthase 1

aminolevulinate synthase H

delta-ALA synthase 1

delta-aminolevulinate synthase 1

succinyl-CoA: glycine C-succinyl transferase

相关产品

Approval
生物活性分子 (2)
目录号 产品名 作用方式
纯度 是否罕见病
HY-132610A Givosiran sodium 98.71% 否
HY-132610 Givosiran 98.51% 否
Pre-clinical Phase
生物活性分子 (3)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-RS00554 ALAS1 Human Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS17599 Alas1 Mouse Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS24059 Alas1 Rat Pre-designed siRNA Set A Pre-designed Set / 否

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Alas1 NCBI NCBI:211
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