1. Gene
  2. Prdx1 - peroxiredoxin 1 Gene

Prdx1 - peroxiredoxin 1 Gene

种属: Rattus norvegicus

同用名: Hbp23

基因 ID: 117254 | 基因类型: protein coding

关于 Prdx1

功能概要

Enables heme binding activity; identical protein binding activity; and peroxiredoxin activity. Involved in response to oxidative stress. Located in several cellular components, including euchromatin; mitochondrial matrix; and peroxisomal matrix. Human ortholog(s) of this gene implicated in methylmalonic aciduria and homocystinuria type cblC. Orthologous to human PRDX1 (peroxiredoxin 1). [provided by Alliance of Genome Resources, Apr 2022]

Prdx1 基因产物(1)

mRNA Protein Name
NM_057114.3 NP_476455.1 peroxiredoxin-1
基因本体论
  • 分子功能
  • 生物过程
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables heme binding IPI
IPI: 通过物理相互作用推断
7577926 RGD
enables identical protein binding IPI
IPI: 通过物理相互作用推断
10535922 RGD
enables peroxiredoxin activity IDA
IDA: 通过直接分析推断
7488219 RGD
生物过程 GO 注释 逻辑证据 参考文献 来源
involved in response to oxidative stress IDA
IDA: 通过直接分析推断
17556052 RGD
细胞组分 GO 注释 逻辑证据 参考文献 来源
located in euchromatin IDA
IDA: 通过直接分析推断
14623930 RGD
located in mitochondrial matrix IDA
IDA: 通过直接分析推断
14623930 RGD
located in peroxisomal matrix IDA
IDA: 通过直接分析推断
14623930 RGD
EXP:通过实验结果推断 IDA:通过直接分析推断 IPI:通过物理相互作用推断 IMP:通过突变表型推断 IGI:通过遗传相互作用推断 IEP:通过表达模式推断
蛋白主名 其他名称

peroxiredoxin-1

heme-binding 23 kDa protein

thioredoxin peroxidase 2

thioredoxin-dependent peroxide reductase 2

thioredoxin-dependent peroxiredoxin 1

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Prdx1 NCBI NCBI:5052
Mus musculus Prdx1 NCBI NCBI:18477