2. Gene
  3. Cenpa - centromere protein A Gene

Cenpa - centromere protein A Gene

  • 基因
  • 蛋白
  • 相关产品
  • 直系同源

种属: Mus musculus

同用名: Cenp-A

基因 ID: 12615 | 基因类型: protein coding

关于 Cenpa

功能概要

Centromeres are the differentiated chromosomal domains that specify the mitotic behavior of chromosomes. This gene encodes a centromere protein which contains a histone H3 related histone fold domain that is required for targeting to the centromere. Centromere protein A is proposed to be a component of a modified nucleosome or nucleosome-like structure in which it replaces 1 or both copies of conventional histone H3 in the (H3-H4)2 tetrameric core of the nucleosome particle. The protein is a replication-independent histone that is a member of the histone H3 family. Alternative splicing results in multiple transcript variants encoding distinct isoforms. [provided by RefSeq, Nov 2015]

Cenpa 基因产物(5)

mRNA Protein Name
NM_001302129.1 NP_001289058.1 histone H3-like centromeric protein A isoform 2
NM_001302130.1 NP_001289059.1 histone H3-like centromeric protein A isoform 2
NM_001302131.1 NP_001289060.1 histone H3-like centromeric protein A isoform 2
NM_001302132.1 NP_001289061.1 histone H3-like centromeric protein A isoform 3
NM_007681.3 NP_031707.1 histone H3-like centromeric protein A isoform 1
基因本体论
  • 生物过程
  • 细胞组分
生物过程 GO 注释 逻辑证据 参考文献 来源
acts upstream of or within protein localization to chromosome, centromeric region IMP
IMP: 通过突变表型推断
22516971 MGI
细胞组分 GO 注释 逻辑证据 参考文献 来源
located in CENP-A containing chromatin IDA
IDA: 通过直接分析推断
14519686 MGI
located in chromosome, centromeric region IDA
IDA: 通过直接分析推断
22516971 MGI
located in condensed chromosome, centromeric region IDA
IDA: 通过直接分析推断
15242786 MGI
located in pericentric heterochromatin IDA
IDA: 通过直接分析推断
15242786 MGI
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断
蛋白主名 其他名称

histone H3-like centromeric protein A

centromere autoantigen A

centrosomin A

相关产品

Pre-clinical Phase
生物活性分子 (3)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-RS02473 CENPA Human Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS19662 Cenpa Mouse Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS26155 Cenpa Rat Pre-designed siRNA Set A Pre-designed Set / 否

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Cenpa NCBI NCBI:1058
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