1. Gene
  2. Smc3 - structural maintenance of chromosomes 3 Gene

Smc3 - structural maintenance of chromosomes 3 Gene

种属: Mus musculus

同用名: HCAP; SmcD; Cspg6; Mmip1; SMC-3; Bamacan

基因 ID: 13006 | 基因类型: protein coding

关于 Smc3

功能概要

Enables chromatin binding activity and mediator complex binding activity. Acts upstream of or within meiotic cell cycle and stem cell population maintenance. Located in lateral element. Part of nuclear meiotic cohesin complex. Is expressed in several structures, including alimentary system; genitourinary system; integumental system; nervous system; and respiratory system. Human ortholog(s) of this gene implicated in Cornelia de Lange syndrome 3. Orthologous to human SMC3 (structural maintenance of chromosomes 3). [provided by Alliance of Genome Resources, Apr 2022]

Smc3 基因产物(1)

mRNA Protein Name
NM_007790.3 NP_031816.2 structural maintenance of chromosomes protein 3
基因本体论
  • 分子功能
  • 生物过程
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables chromatin binding IDA
IDA: 通过直接分析推断
20720539 MGI
enables cis-regulatory region sequence-specific DNA binding IDA
IDA: 通过直接分析推断
28636939 MGI
enables mediator complex binding IDA
IDA: 通过直接分析推断
20720539 MGI
enables protein binding IPI
IPI: 通过物理相互作用推断
10375619 MGI
生物过程 GO 注释 逻辑证据 参考文献 来源
acts upstream of or within meiotic cell cycle IPI
IPI: 通过物理相互作用推断
12759374 MGI
acts upstream of or within stem cell population maintenance IMP
IMP: 通过突变表型推断
20720539 MGI
细胞组分 GO 注释 逻辑证据 参考文献 来源
part of cohesin complex IDA
IDA: 通过直接分析推断
10375619 MGI
located in lateral element IDA
IDA: 通过直接分析推断
15870106 MGI
part of meiotic cohesin complex IDA
IDA: 通过直接分析推断
21527826 MGI
located in nucleus IDA
IDA: 通过直接分析推断
10375619 MGI
EXP:通过实验结果推断 IDA:通过直接分析推断 IPI:通过物理相互作用推断 IMP:通过突变表型推断 IGI:通过遗传相互作用推断 IEP:通过表达模式推断
蛋白主名 其他名称

structural maintenance of chromosomes protein 3

SMC protein 3

basement membrane-associated chondroitin proteoglycan

chondroitin sulfate proteoglycan 6

chromosome segregation protein SmcD

mad member-interacting protein 1

structural maintenace of chromosomes 3

Smc3 蛋白互作信息

分类
蛋白名称 蛋白编号 互作蛋白 互作蛋白种属 互作蛋白编号 实验方法 参考文献
种属内
Smc3 Q9CW03 Mecp2 Mus musculus Q9Z2D6 20159591
种属间: 跨种属相互作用 种属内: 同种属相互作用

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Smc3 NCBI NCBI:9126