2. Gene
  3. Fasn - fatty acid synthase Gene

Fasn - fatty acid synthase Gene

  • 基因
  • 蛋白
  • 相关产品
  • 直系同源

中文名称：脂肪酸合酶

种属: Mus musculus

同用名: FAS; A630082H08Rik

基因 ID: 14104 | 基因类型: protein coding

关于 Fasn

Chromosome 11: 120,696,672-120,715,373 reverse strand.GRCm39:CM001004.3

This gene has 6 transcripts (splice variants), 195 orthologues, 1 paralogue and is associated with 4 phenotypes. Biased expression in mammary gland adult (RPKM 165.), subcutaneous fat pad adult (RPKM 1125.4) and 6 other tissues.

功能概要

该基因编码的蛋白可启动脂肪酸合酶活性。参与醚类脂类生物合成过程；乳腺发育；和髓样白细胞分化。作用于细胞对 interleukin-4 的反应上游或内部；上皮细胞发育；和脂肪酸的生物合成过程。位于糖原颗粒中。以多种结构表达，包括脂肪组织；消化系统；神经系统;感觉器官；和骨架。与人类 FASN（脂肪酸合成酶）同源。 [由基因组资源联盟提供，2022 年 4 月]

Enables fatty acid synthase activity. Involved in ether lipid biosynthetic process; mammary gland development; and myeloid leukocyte differentiation. Acts upstream of or within cellular response to interleukin-4; epithelial cell development; and fatty acid biosynthetic process. Located in glycogen granule. Is expressed in several structures, including adipose tissue; alimentary system; nervous system; sensory organ; and skeleton. Orthologous to human FASN (fatty acid synthase). [provided by Alliance of Genome Resources, Apr 2022]

Fasn 基因产物(1)

mRNA Protein Name
NM_007988.3 NP_032014.3 fatty acid synthase

Fasn 蛋白结构

PksD

PksD: COG3321 (0 - 1014)

PKS

PKS: cd00833 (1 - 403)

Methyltransf_12

Methyltransf_12: pfam08242 (1238 - 1336)

KR_1_FAS_SDR_x

KR_1_FAS_SDR_x: cd08954 (1310 - 1517)

PKS_ER

PKS_ER: smart00829 (1556 - 1846)

KR_1_FAS_SDR_x

KR_1_FAS_SDR_x: cd08954 (1868 - 2104)

PKS_PP

PKS_PP: smart00823 (2117 - 2172)

Thioesterase

Thioesterase: pfam00975 (2234 - 2493)

  • 0
  • 400
  • 800
  • 1200
  • 1600
  • 2000
  • 2504 a.a.
蛋白主名 其他名称

fatty acid synthase

type I Fatty Acid Synthase

相关产品

Approval
生物活性分子 (1)
目录号 产品名 作用方式
纯度 是否罕见病
HY-B0218 Orlistat 99.97% 否
Clinical Phase
生物活性分子 (1)
目录号 产品名 作用方式
纯度 Phase
HY-112829 Denifanstat Inhibitor 99.69% Phase 3
Pre-clinical Phase
生物活性分子 (34)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-12364 C75 Inhibitor 99.91% 否
HY-120394 TVB-3166 99.76% 否
HY-A0210 Cerulenin 99.52% 否
HY-120062 TVB-3664 Inhibitor 99.57% 否
HY-12325 GSK2194069 Inhibitor 99.84% 否
HY-12364A trans-C75 Inhibitor 99.73% 否
HY-16100 BI 99179 Inhibitor 99.78% 否
HY-124628 IPI-9119 Inhibitor 99.24% 否
HY-12648A FASN-IN-4 tosylate Inhibitor 99.84% 否
HY-111551 FT113 Inhibitor 99.61% 否
HY-N2486 Desoxyrhaponticin 99.80% 否
HY-121250 Fasnall 99.54% 否
HY-133180 YW1128 Inhibitor 99.38% 否
HY-110354 UCM05 Inhibitor 99.58% 否
HY-RS04754 Fasn Mouse Pre-designed siRNA Set A Pre-designed Sets / 否
HY-12648 FASN-IN-4 Inhibitor 99.21% 否
HY-111777 FASN-IN-1 Inhibitor 99.90% 否
HY-117769 GSK837149A Inhibitor ≥99.0% 否
HY-B0218R Orlistat (Standard) 99.85% 否
HY-U00436 FASN-IN-3 Inhibitor 98.06% 否
HY-158820 Cosdosiran / 否
HY-158820A Cosdosiran sodium / 否
HY-12364B (−)-C75 Inhibitor / 否
HY-145809 FASN-IN-5 Inhibitor 99.81% 否
HY-149540 CTL-06 Inhibitor / 否
HY-149541 CTL-12 Inhibitor / 否
HY-155282 FASN-IN-6 Inhibitor / 否
HY-E70364 IgdE protease / 否
HY-N8144 Niga-ichigoside F1 ≥99.0% 否
HY-RS04753 FASN Human Pre-designed siRNA Set A Pre-designed Sets / 否
HY-RS04755 Fasn Rat Pre-designed siRNA Set A Pre-designed Sets / 否
HY-B0218S Orlistat-d3 / 否
HY-112522 HS79 Inhibitor / 否
HY-112522A HS80 Inhibitor / 否

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Fasn NCBI NCBI:2194
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