2. Gene
  3. Fzd1 - frizzled class receptor 1 Gene

Fzd1 - frizzled class receptor 1 Gene

  • 基因
  • 蛋白
  • 相关产品
  • 直系同源

种属: Mus musculus

同用名: Fz1; FZ-1

基因 ID: 14362 | 基因类型: protein coding

关于 Fzd1

功能概要

Enables Wnt-protein binding activity. Involved in astrocyte-dopaminergic neuron signaling; negative regulation of oxidative stress-induced neuron death; and regulation of presynapse assembly. Acts upstream of or within several processes, including Wnt signaling pathway; heart morphogenesis; and negative regulation of signal transduction. Predicted to be located in cell surface and neuron projection. Predicted to be active in plasma membrane. Predicted to be integral component of membrane. Is expressed in several structures, including alimentary system; central nervous system; genitourinary system; immune system; and sensory organ. Orthologous to human FZD1 (Frizzled class receptor 1). [provided by Alliance of Genome Resources, Apr 2022]

Fzd1 基因产物(1)

mRNA Protein Name
NM_021457.3 NP_067432.2 frizzled-1 precursor
基因本体论
  • 分子功能
  • 生物过程
分子功能 GO 注释 逻辑证据 参考文献 来源
enables Wnt-protein binding IPI
IPI: 通过物理相互作用推断
15923619 MGI
生物过程 GO 注释 逻辑证据 参考文献 来源
acts upstream of or within canonical Wnt signaling pathway IGI
IGI: 通过遗传相互作用推断
15923619 MGI
acts upstream of or within canonical Wnt signaling pathway IMP
IMP: 通过突变表型推断
15143170 MGI
acts upstream of or within cell-cell signaling IDA
IDA: 通过直接分析推断
15809042 MGI
acts upstream of or within endothelial cell differentiation IDA
IDA: 通过直接分析推断
15809042 MGI
acts upstream of or within endothelial cell differentiation IGI
IGI: 通过遗传相互作用推断
15809042 MGI
acts upstream of or within hard palate development IGI
IGI: 通过遗传相互作用推断
20940229 MGI
acts upstream of or within membranous septum morphogenesis IGI
IGI: 通过遗传相互作用推断
20940229 MGI
acts upstream of or within muscular septum morphogenesis IGI
IGI: 通过遗传相互作用推断
20940229 MGI
acts upstream of or within negative regulation of BMP signaling pathway IDA
IDA: 通过直接分析推断
14627707 MGI
acts upstream of or within negative regulation of DNA-templated transcription IMP
IMP: 通过突变表型推断
16936075 MGI
acts upstream of or within negative regulation of canonical Wnt signaling pathway IDA
IDA: 通过直接分析推断
14627707 MGI
involved in negative regulation of oxidative stress-induced neuron intrinsic apoptotic signaling pathway IMP
IMP: 通过突变表型推断
21752258 MGI
acts upstream of or within outflow tract morphogenesis IGI
IGI: 通过遗传相互作用推断
20940229 MGI
acts upstream of or within positive regulation of protein phosphorylation IMP
IMP: 通过突变表型推断
15143170 MGI
involved in regulation of presynapse assembly IDA
IDA: 通过直接分析推断
19883499 MGI
involved in regulation of presynapse assembly IMP
IMP: 通过突变表型推断
19883499 MGI
acts upstream of or within ventricular septum morphogenesis IGI
IGI: 通过遗传相互作用推断
20940229 MGI
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断
蛋白主名 其他名称

frizzled-1

frizzled homolog 1

mFz1

重组 Fzd1 蛋白

目录号 产品名 蛋白编号 纯度
HY-P70210 Frizzled-1 Protein, Mouse (HEK293, Fc) O70421 (V69-H248) ≥95%

相关产品

Clinical Phase
抗体抑制剂 (1)
目录号 产品名 作用方式
纯度 Phase
HY-P9974 Vantictumab Inhibitor 99.40% Phase 1
Pre-clinical Phase
生物活性分子 (3)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-RS05176 FZD1 Human Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS18358 Fzd1 Mouse Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS24837 Fzd1 Rat Pre-designed siRNA Set A Pre-designed Set / 否

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Fzd1 NCBI NCBI:8321
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