1. Gene
  2. Gal - galanin and GMAP prepropeptide Gene

Gal - galanin and GMAP prepropeptide Gene

种属: Mus musculus

同用名: Galn

基因 ID: 14419 | 基因类型: protein coding

关于 Gal

功能概要

This gene encodes a neuroendocrine peptide that is principally produced by a subpopulation of lactotrophs in the pituitary gland. The encoded protein is a precursor that is proteolytically processed to generate two mature peptides: Galanin and Galanin message-associated peptide (GMAP). Mice lacking the encoded protein fail to lactate sufficiently due to abnormalities in the expression of Prolactin and lactotroph proliferation, exhibit attenuated chronic neuropathic pain and developmental deficits in the dorsal root ganglion neurons. This gene encodes distinct isoforms, some or all of which may undergo similar processing to generate the mature proteins. [provided by RefSeq, Jul 2016]

Gal 基因产物(2)

mRNA Protein Name
NM_001329667.1 NP_001316596.1 galanin peptides isoform 2 precursor
NM_010253.4 NP_034383.1 galanin peptides isoform 1 preproprotein
蛋白主名 其他名称

galanin peptides

galanin

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Gal NCBI NCBI:51083
Macaca fascicularis Gal NCBI NCBI:102144812
Rattus norvegicus Gal NCBI NCBI:29141