2. Gene
  3. Hcn2 - hyperpolarization-activated, cyclic nucleotide-gated K+ 2 Gene

Hcn2 - hyperpolarization-activated, cyclic nucleotide-gated K+ 2 Gene

  • 基因
  • 蛋白
  • 相关产品
  • 直系同源

种属: Mus musculus

同用名: HAC1; trls; BCNG2

基因 ID: 15166 | 基因类型: protein coding

关于 Hcn2

功能概要

Predicted to enable several functions, including PDZ domain binding activity; cation channel activity; and identical protein binding activity. Acts upstream of or within regulation of membrane potential. Predicted to be located in several cellular components, including axon; dendrite; and neuronal cell body. Predicted to be integral component of plasma membrane. Predicted to be part of HCN Channel complex. Is expressed in heart; heart ventricle; spinal cord; and ventral grey horn. Human ortholog(s) of this gene implicated in familial febrile seizures 2. Orthologous to human HCN2 (hyperpolarization activated cyclic nucleotide gated potassium and Sodium Channel 2). [provided by Alliance of Genome Resources, Apr 2022]

Hcn2 基因产物(1)

mRNA Protein Name
NM_008226.2 NP_032252.1 potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 2
基因本体论
  • 分子功能
  • 生物过程
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables protein binding IPI
IPI: 通过物理相互作用推断
15564593 MGI
生物过程 GO 注释 逻辑证据 参考文献 来源
acts upstream of or within regulation of membrane potential IDA
IDA: 通过直接分析推断
15564593 MGI
acts upstream of or within regulation of membrane potential IGI
IGI: 通过遗传相互作用推断
15564593 MGI
细胞组分 GO 注释 逻辑证据 参考文献 来源
located in membrane IDA
IDA: 通过直接分析推断
30886335 MGI
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断
蛋白主名 其他名称

potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 2

BCNG-2

HAC-1

brain cyclic nucleotide-gated channel 2

hyperpolarization-activated cation channel 1

Hcn2 蛋白互作信息

分类
蛋白名称 蛋白编号 互作蛋白 互作蛋白种属 互作蛋白编号 实验方法 参考文献
种属间
Hcn2 O88703 SRC Gallus gallus P00523
Y2H
16079136
种属间
Hcn2 O88703 SRC Gallus gallus P00523
Pull Down
16079136
种属间: 跨种属相互作用 种属内: 同种属相互作用

相关产品

Clinical Phase
生物活性分子 (1)
目录号 产品名 作用方式
纯度 Phase
HY-18940 Cilobradine / Phase 2
Pre-clinical Phase
生物活性分子 (6)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-13422 Zatebradine hydrochloride Antagonist 99.87% 否
HY-13422A Zatebradine Antagonist 99.27% 否
HY-160505 RO-275 Inhibitor ≥99.0% 否
HY-RS06047 HCN2 Human Pre-designed siRNA Set A Pre-designed Sets / 否
HY-RS18617 Hcn2 Mouse Pre-designed siRNA Set A Pre-designed Sets / 否
HY-RS25103 Hcn2 Rat Pre-designed siRNA Set A Pre-designed Sets / 否

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Hcn2 NCBI NCBI:610
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