2. Gene
  3. Hk1 - hexokinase 1 Gene

Hk1 - hexokinase 1 Gene

  • 基因
  • 蛋白
  • 相关产品
  • 直系同源

种属: Mus musculus

同用名: dea; Hk-1; Hk1-s; mHk1-s

基因 ID: 15275 | 基因类型: protein coding

关于 Hk1

功能概要

Enables Glucokinase activity and peptidoglycan binding activity. Involved in carbohydrate phosphorylation; positive regulation of cytokine production involved in immune response; and positive regulation of interleukin-1 beta production. Located in several cellular components, including membrane raft; mitochondrion; and sperm principal piece. Is expressed in several structures, including alimentary system; integumental system; nervous system; respiratory system; and sensory organ. Human ortholog(s) of this gene implicated in Charcot-Marie-Tooth disease type 4G; anemia (multiple); hematologic Cancer (multiple); obesity; and retinitis pigmentosa. Orthologous to human HK1 (Hexokinase 1). [provided by Alliance of Genome Resources, Apr 2022]

Hk1 基因产物(2)

mRNA Protein Name
NM_001146100.1 NP_001139572.1 hexokinase-1 isoform HK1
NM_010438.3 NP_034568.2 hexokinase-1 isoform HK1-sb
基因本体论
  • 分子功能
  • 生物过程
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables glucokinase activity IDA
IDA: 通过直接分析推断
18509164 MGI
enables hexokinase activity IDA
IDA: 通过直接分析推断
15155459 MGI
enables hexokinase activity IMP
IMP: 通过突变表型推断
27374331 MGI
enables peptidoglycan binding IDA
IDA: 通过直接分析推断
27374331 MGI
enables protein binding IPI
IPI: 通过物理相互作用推断
19889946 MGI
生物过程 GO 注释 逻辑证据 参考文献 来源
involved in GDP-mannose biosynthetic process from glucose IDA
IDA: 通过直接分析推断
21273394 MGI
involved in GDP-mannose biosynthetic process from mannose IDA
IDA: 通过直接分析推断
21273394 MGI
involved in canonical glycolysis IDA
IDA: 通过直接分析推断
4275392 MGI
involved in carbohydrate phosphorylation IMP
IMP: 通过突变表型推断
27374331 MGI
involved in positive regulation of cytokine production involved in immune response IDA
IDA: 通过直接分析推断
27374331 MGI
involved in positive regulation of interleukin-1 beta production IDA
IDA: 通过直接分析推断
27374331 MGI
细胞组分 GO 注释 逻辑证据 参考文献 来源
is active in cytosol IDA
IDA: 通过直接分析推断
12420306 MGI
located in cytosol IDA
IDA: 通过直接分析推断
12420306 MGI
located in membrane raft IDA
IDA: 通过直接分析推断
19144954 MGI
located in mitochondrion IDA
IDA: 通过直接分析推断
27374331 MGI
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断
蛋白主名 其他名称

hexokinase-1

HK I

downeast anemia

hexokinase type I

hexokinase, tumor isozyme

相关产品

Pre-clinical Phase
生物活性分子 (8)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-N6954 Garcinone C 99.66% 否
HY-RS06192 HK1 Human Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS06287 HOOK1 Human Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS07100 KCNA4 Human Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS07373 KLK1 Human Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS14138 TAC4 Human Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS17121 Hk1 Mouse Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS23566 Hk1 Rat Pre-designed siRNA Set A Pre-designed Set / 否

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Hk1 NCBI NCBI:3098
Macaca fascicularis Hk1 NCBI NCBI:102145864
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