1. Gene
  2. Hp - haptoglobin Gene

Hp - haptoglobin Gene

种属: Mus musculus

同用名: HP-1; preHP2

基因 ID: 15439 | 基因类型: protein coding

关于 Hp

功能概要

This gene encodes a plasma glycoprotein called haptoglobin that binds free Hemoglobin. The encoded preproprotein undergoes proteolytic processing to generate alpha and beta subunits that form a disulfide-linked tetrameric protein that plays an important role in the sequestration and clearance of extracorpuscular Hemoglobin. Mice lacking the encoded protein exhibit stunted development of lymphoid organs associated with lower counts of mature T and B cells in the blood and secondary lymphoid compartments. [provided by RefSeq, Aug 2016]

Hp 基因产物(2)

mRNA Protein Name
NM_001329965.1 NP_001316894.1 haptoglobin isoform 2 precursor
NM_017370.2 NP_059066.1 haptoglobin isoform 1 preproprotein
基因本体论
  • 生物过程
生物过程 GO 注释 逻辑证据 参考文献 来源
acts upstream of or within Notch signaling pathway IDA
IDA: 通过直接分析推断
23117660 MGI
acts upstream of or within response to bacterium IEP
IEP: 通过表达模式推断
23012479 MGI
EXP:通过实验结果推断 IDA:通过直接分析推断 IPI:通过物理相互作用推断 IMP:通过突变表型推断 IGI:通过遗传相互作用推断 IEP:通过表达模式推断
蛋白主名 其他名称

haptoglobin

zonulin

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Hp NCBI NCBI:3240
Canis familiaris Hp NCBI
Felis catus Hp NCBI NCBI:100144610
Macaca fascicularis Hp NCBI
Susscrofa domestica Hp NCBI
Rattus norvegicus Hp NCBI NCBI:24464
Macaca mulatta Hp NCBI NCBI:706640