2. Gene
  3. Id1 - inhibitor of DNA binding 1, HLH protein Gene

Id1 - inhibitor of DNA binding 1, HLH protein Gene

  • 基因
  • 蛋白
  • 相关产品
  • 直系同源

种属: Mus musculus

同用名: Idb1; bHLHb24; D2Wsu140e

基因 ID: 15901 | 基因类型: protein coding

关于 Id1

功能概要

Enables protein self-association and transcription regulator inhibitor activity. Involved in negative regulation of cold-induced thermogenesis; negative regulation of transcription, DNA-templated; and positive regulation of gene expression. Acts upstream of or within several processes, including endothelial cell morphogenesis; lung development; and negative regulation of macromolecule metabolic process. Located in cytoplasm and nucleus. Is expressed in several structures, including alimentary system; central nervous system; embryo mesenchyme; genitourinary system; and sensory organ. Orthologous to human ID1 (inhibitor of DNA binding 1, HLH protein). [provided by Alliance of Genome Resources, Apr 2022]

Id1 基因产物(3)

mRNA Protein Name
NM_001355113.1 NP_001342042.1 DNA-binding protein inhibitor ID-1 isoform 1
NM_001369018.1 NP_001355947.1 DNA-binding protein inhibitor ID-1 isoform 3
NM_010495.3 NP_034625.1 DNA-binding protein inhibitor ID-1 isoform 2
基因本体论
  • 分子功能
  • 生物过程
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables protein binding IPI
IPI: 通过物理相互作用推断
1922066 MGI
enables transcription regulator inhibitor activity IDA
IDA: 通过直接分析推断
17681138 MGI
生物过程 GO 注释 逻辑证据 参考文献 来源
acts upstream of or within BMP signaling pathway IDA
IDA: 通过直接分析推断
15820682 MGI
acts upstream of apoptotic process IMP
IMP: 通过突变表型推断
17717145 MGI
involved in circadian rhythm IEP
IEP: 通过表达模式推断
19217292 MGI
acts upstream of or within collagen metabolic process IMP
IMP: 通过突变表型推断
17717145 MGI
acts upstream of endothelial cell apoptotic process IMP
IMP: 通过突变表型推断
17717145 MGI
acts upstream of or within endothelial cell morphogenesis IMP
IMP: 通过突变表型推断
17717145 MGI
acts upstream of or within heart development IGI
IGI: 通过遗传相互作用推断
15472070 MGI
acts upstream of or within lung morphogenesis IMP
IMP: 通过突变表型推断
17717145 MGI
acts upstream of or within lung vasculature development IMP
IMP: 通过突变表型推断
17717145 MGI
acts upstream of or within negative regulation of DNA binding IDA
IDA: 通过直接分析推断
1922066 MGI
involved in negative regulation of DNA-templated transcription IDA
IDA: 通过直接分析推断
19217292 MGI
involved in negative regulation of cold-induced thermogenesis IMP
IMP: 通过突变表型推断
28270523 MGI
acts upstream of or within negative regulation of endothelial cell apoptotic process IMP
IMP: 通过突变表型推断
17717145 MGI
acts upstream of or within negative regulation of gene expression IMP
IMP: 通过突变表型推断
20231428 MGI
acts upstream of or within negative regulation of osteoblast differentiation IGI
IGI: 通过遗传相互作用推断
15161906 MGI
acts upstream of or within negative regulation of transcription by RNA polymerase II IDA
IDA: 通过直接分析推断
12498716 MGI
acts upstream of or within negative regulation of transcription by RNA polymerase II IGI
IGI: 通过遗传相互作用推断
19217292 MGI
involved in positive regulation of gene expression IDA
IDA: 通过直接分析推断
17681138 MGI
involved in positive regulation of gene expression IGI
IGI: 通过遗传相互作用推断
17681138 MGI
acts upstream of or within protein destabilization IDA
IDA: 通过直接分析推断
15322112 MGI
acts upstream of or within protein destabilization IGI
IGI: 通过遗传相互作用推断
15322112 MGI
acts upstream of or within regulation of MAPK cascade IMP
IMP: 通过突变表型推断
17717145 MGI
acts upstream of or within regulation of angiogenesis IMP
IMP: 通过突变表型推断
12498716 MGI
acts upstream of or within response to antibiotic IMP
IMP: 通过突变表型推断
17717145 MGI
细胞组分 GO 注释 逻辑证据 参考文献 来源
located in cytoplasm IDA
IDA: 通过直接分析推断
9418957 MGI
located in nucleus IDA
IDA: 通过直接分析推断
15322112 MGI
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断
蛋白主名 其他名称

DNA-binding protein inhibitor ID-1

inhibitor of differentiation 1

相关产品

Pre-clinical Phase
生物活性分子 (8)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-124697 BMP signaling agonist sb4 Agonist 99.98% 否
HY-129241 AGX51 Antagonist 99.33% 否
HY-80012 SJB3-019A Inhibitor 99.88% 否
HY-110245 DMH2 Inducer 99.6% 否
HY-RS06522 ID1 Human Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS06528 Idh1 Mouse Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS16689 Id1 Mouse Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS23124 Id1 Rat Pre-designed siRNA Set A Pre-designed Set / 否

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Id1 NCBI NCBI:3397
Rattus norvegicus Id1 NCBI NCBI:25261
Macaca mulatta Id1 NCBI NCBI:713160
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